Banu Ayesha, Salim Safa, Mohammad Farhan
College of Health & Life Sciences (CHLS), Hamad Bin Khalifa University (HBKU), Doha 34110, Qatar.
Biology (Basel). 2025 Sep 2;14(9):1168. doi: 10.3390/biology14091168.
has been a cornerstone of biological research, offering critical insights into genetics, neurobiology, and disease modelling. This review examines feeding research, including the diverse assays available to study feeding behaviour, and explores its biomedical and entomological applications. We highlight studies that have advanced our understanding of human feeding and eating disorders, vector-borne infectious diseases, and agricultural pest control. In clinical applications, we discuss a two-pronged approach: using to model human feeding and eating disorders, as well as to study insect vectors that contribute to human disease transmission. We explore how feeding studies in provide valuable insights into energy homeostasis, metabolic regulation, pathogen-host interactions, and vector biology. Beyond clinical relevance, the entomological applications of feeding research extend to sustainable pest management and insecticide resistance. Finally, we identify gaps in current research and suggest promising directions for further exploration. By leveraging the genetic and behavioural tools available in this model, researchers can continue to uncover conserved mechanisms with broad implications for human health, disease control, and agricultural sustainability.
一直是生物学研究的基石,为遗传学、神经生物学和疾病建模提供了关键见解。本综述考察了进食研究,包括可用于研究进食行为的多种分析方法,并探讨了其在生物医学和昆虫学方面的应用。我们重点介绍了那些增进我们对人类进食和饮食失调、媒介传播传染病以及农业害虫控制理解的研究。在临床应用中,我们讨论了一种双管齐下的方法:利用其对人类进食和饮食失调进行建模,以及研究导致人类疾病传播的昆虫媒介。我们探讨了在该模型中的进食研究如何为能量稳态、代谢调节、病原体 - 宿主相互作用和媒介生物学提供有价值的见解。除了临床相关性,该模型进食研究的昆虫学应用还扩展到可持续害虫管理和抗药性方面。最后,我们确定了当前研究中的差距,并提出了进一步探索的有前景的方向。通过利用该模型中可用的遗传和行为工具,研究人员可以继续揭示具有广泛意义的保守机制,这些机制对人类健康、疾病控制和农业可持续性具有重要意义。