Pineda Vanessa, Calzada Jose E, Montilla Santiago, Rodríguez Indra, Howard Erika, Torres Alicia I, Vasquez Vanessa, Reina Adelys, Saldaña Azael, González Kadir
Departamento de Investigación en Parasitología, Instituto Conmemorativo Gorgas de Estudios de la Salud, Panama 0816-02593, Panama.
Facultad de Medicina Veterinaria, Universidad de Panama, Panama 0816-03366, Panama.
Animals (Basel). 2025 Sep 12;15(18):2677. doi: 10.3390/ani15182677.
(CL) is a vector-borne zoonotic disease affecting the skin and mucous membranes of animals and humans. While CL is commonly diagnosed and studied in humans in Panama, limited information exists on its occurrence in domestic animals and their potential role as reservoirs. In this study, samples from twelve domestic animals (ten dogs and two horses) with suspected CL lesions were collected between 2021 and 2025 in endemic regions of Panama and evaluated using multiple diagnostic methods. infection was confirmed in six of them (50%): five dogs and one horse. Three dogs were infected with () , representing the first molecularly confirmed cases of this species in dogs from Panama and Central America. Two dogs tested positive for () though epidemiological evidence suggests these were imported cases. Notably, () was identified in a horse, marking the first report of this species in equines in Central America. These findings indicate a broader diversity of species circulating in domestic animals than previously recognized and highlight their potential role in sustaining transmission cycles. The study underscores the need for enhanced surveillance of animal reservoirs to better understand the epidemiology and public health risks of CL in Panama.
皮肤利什曼病是一种由媒介传播的人畜共患病，会影响动物和人类的皮肤及黏膜。虽然在巴拿马，皮肤利什曼病在人类中常被诊断和研究，但关于其在家畜中的发生情况及其作为宿主的潜在作用的信息有限。在本研究中，于2021年至2025年期间在巴拿马的流行地区收集了12只患有疑似皮肤利什曼病病变的家畜（10只狗和2匹马）的样本，并使用多种诊断方法进行评估。其中6只（50%）被确诊感染：5只狗和1匹马。3只狗感染了（某种利什曼原虫），这是巴拿马和中美洲犬类中该物种的首批分子确诊病例。2只狗经检测对（另一种利什曼原虫）呈阳性，不过流行病学证据表明这些是输入性病例。值得注意的是，在一匹马身上发现了（又一种利什曼原虫），这是中美洲马类中该物种的首次报告。这些发现表明，在家畜中传播的利什曼原虫物种比之前认识到的更加多样，并突出了它们在维持传播循环中的潜在作用。该研究强调需要加强对动物宿主的监测，以更好地了解巴拿马皮肤利什曼病的流行病学和公共卫生风险。
