Rocks Damian L, Sharpley Christopher F, Bitsika Vicki, Vessey Kirstan A, Odierna G Lorenzo, Watson Christopher B
Brain-Behaviour Research Group, University of New England, Armidale, NSW 2351, Australia.
Brain Sci. 2025 Sep 2;15(9):957. doi: 10.3390/brainsci15090957.
Because of their potential to enhance pathways for diagnosis and treatment, a great deal of research has been conducted to identify brain biomarkers of mental illnesses such as depression and anxiety. Similarly, the investigation of the biomarkers of those protective factors that help individuals resist, or recover from, these mental illnesses is also directly relevant to clinical practice. One such protective factor is Psychological Resilience (PR) but relatively little is known about its neurobiological underpinnings. A literature search was conducted of electroencephalographic data and PR, revealing seven studies that reported brain electrical activity categorised into bands of specified frequencies. Several studies reported significant associations between PR and alpha band activity, and somewhat less on beta band activity, principally via their roles in emotion regulation and problem solving. However, despite having a major role in many aspects of cognition and brain function, and being implicated in depression, only two studies examined gamma band activity specifically, and their results were equivocal. Several possible reasons for these apparently null results of the association between gamma band activity and PR are discussed, leading to a brief description of gamma, and suggestions for future research into its association with PR.
由于其在增强诊断和治疗途径方面的潜力，人们开展了大量研究以确定抑郁症和焦虑症等精神疾病的脑生物标志物。同样，对那些有助于个体抵抗或从这些精神疾病中康复的保护因素的生物标志物进行研究也与临床实践直接相关。心理韧性（PR）就是这样一种保护因素，但对其神经生物学基础的了解相对较少。我们对脑电图数据和心理韧性进行了文献检索，发现七项研究报告了被分类为特定频率波段的脑电活动。几项研究报告了心理韧性与α波段活动之间存在显著关联，而与β波段活动的关联则稍少，主要是通过它们在情绪调节和问题解决中的作用。然而，尽管γ波段在认知和脑功能的许多方面发挥着重要作用，且与抑郁症有关，但只有两项研究专门考察了γ波段活动，其结果并不明确。本文讨论了γ波段活动与心理韧性之间关联的这些明显无效结果的几个可能原因，对γ波段进行了简要描述，并对其与心理韧性关联的未来研究提出了建议。
