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单腔还是双腔抽吸针?重新审视体外受精或卵胞浆内单精子注射的选择——一项批判性综述。

Single or Double-Lumen Aspiration Needle? Revisiting Choices for In Vitro Fertilization or Intracytoplasmic Sperm Injection-A Critical Review.

作者信息

Muruti Gopinath, Ahmad Mohd Faizal, Abu Muhammad Azrai, Latif Nurul Ilani Abdul, Karim Abdul Kadir Abdul

机构信息

Advanced Reproductive Centre, Hospital Canselor Tuanku Muhriz, National University of Malaysia, Kuala Lumpur 56000, Malaysia.

Department of Obstetrics & Gynaecology, Faculty of Medicine, National University of Malaysia, Kuala Lumpur 56000, Malaysia.

出版信息

Life (Basel). 2025 Aug 22;15(9):1334. doi: 10.3390/life15091334.

DOI:10.3390/life15091334
PMID:41010276
Abstract

Transvaginal ultrasound-guided follicle aspiration remains the gold standard for oocyte retrieval in assisted reproductive technology (ART). This procedure employs either a single-lumen aspiration needle (SLN) or double-lumen aspiration needle (DLN), both of which are effective modalities for oocyte retrieval. The primary objective of this review is to systematically compare the impact and clinical outcomes associated with the use of SLN versus DLN in women undergoing ART. A systematic literature search was conducted across two databases, PubMed and Google Scholar, encompassing publications from their inception until May 2025, and articles published in English. A total of five studies were included in the final analysis. The oocyte yield and the number of MII oocyte did not differ significantly between the groups. Procedural duration was markedly shorter in the SLN group compared to the DLN group. No significant differences were observed in procedure-related complications across groups. Two randomized controlled trials reported comparable fertilization rates and numbers of high-quality embryos between the two needle types. Additionally, clinical pregnancy rates, ongoing pregnancy rates, and live birth rates were similar between the SLN and DLN groups. In conclusion, the utilization ofan SLN for oocyte retrieval demonstrates comparable efficacy to that of a DLN.

摘要

经阴道超声引导下卵泡抽吸术仍是辅助生殖技术(ART)中获取卵母细胞的金标准。该手术采用单腔抽吸针(SLN)或双腔抽吸针(DLN),两者都是获取卵母细胞的有效方式。本综述的主要目的是系统比较在接受ART的女性中使用SLN与DLN的影响和临床结果。在PubMed和谷歌学术这两个数据库中进行了系统的文献检索,涵盖从数据库创建到2025年5月的出版物以及以英文发表的文章。最终分析共纳入五项研究。两组之间的卵母细胞产量和MII期卵母细胞数量无显著差异。与DLN组相比,SLN组的手术时间明显更短。各组之间在与手术相关的并发症方面未观察到显著差异。两项随机对照试验报告了两种针型之间可比的受精率和高质量胚胎数量。此外,SLN组和DLN组之间的临床妊娠率、持续妊娠率和活产率相似。总之,使用SLN获取卵母细胞显示出与DLN相当的疗效。

相似文献

1
Single or Double-Lumen Aspiration Needle? Revisiting Choices for In Vitro Fertilization or Intracytoplasmic Sperm Injection-A Critical Review.单腔还是双腔抽吸针?重新审视体外受精或卵胞浆内单精子注射的选择——一项批判性综述。
Life (Basel). 2025 Aug 22;15(9):1334. doi: 10.3390/life15091334.
2
Follicular flushing during oocyte retrieval in assisted reproductive techniques.辅助生殖技术中取卵时的卵泡冲洗
Cochrane Database Syst Rev. 2018 Apr 26;4(4):CD004634. doi: 10.1002/14651858.CD004634.pub3.
3
Day three versus day two embryo transfer following in vitro fertilization or intracytoplasmic sperm injection.体外受精或卵胞浆内单精子注射后第三天与第二天胚胎移植的比较。
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Individualised gonadotropin dose selection using markers of ovarian reserve for women undergoing in vitro fertilisation plus intracytoplasmic sperm injection (IVF/ICSI).针对接受体外受精加卵胞浆内单精子注射(IVF/ICSI)的女性,使用卵巢储备标志物进行个性化促性腺激素剂量选择。
Cochrane Database Syst Rev. 2018 Feb 1;2(2):CD012693. doi: 10.1002/14651858.CD012693.pub2.
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Follicular flushing during oocyte retrieval in assisted reproductive techniques.在辅助生殖技术中取卵时卵泡冲血。
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Oocyte activation for women following intracytoplasmic sperm injection (ICSI).卵胞浆内单精子注射(ICSI)后女性的卵母细胞激活。
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Follicular flushing during oocyte retrieval in assisted reproductive techniques.辅助生殖技术中取卵时的卵泡冲洗
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本文引用的文献

1
Introduction of the single-lumen oocyte retrieval needle in an assisted reproductive technology center: Propensity score matching analysis of grouping.单腔卵母细胞取卵针在辅助生殖技术中心的引入:分组的倾向评分匹配分析
Taiwan J Obstet Gynecol. 2025 Jan;64(1):105-109. doi: 10.1016/j.tjog.2024.03.027.
2
A Monocentric Randomized Controlled Clinical Trial to Compare Single- and Double-Lumen Needles in Oocyte Retrieval Procedure in Assisted Reproductive Technologies.一项比较在辅助生殖技术中卵母细胞采集程序中单腔和双腔针的单中心随机对照临床试验。
Reprod Sci. 2023 Sep;30(9):2866-2875. doi: 10.1007/s43032-023-01232-w. Epub 2023 Apr 17.
3
The importance of follicular flushing in optimizing oocyte retrieval.
卵泡冲洗在优化卵母细胞获取中的重要性。
Curr Opin Obstet Gynecol. 2023 Jun 1;35(3):238-245. doi: 10.1097/GCO.0000000000000870. Epub 2023 Mar 17.
4
Causes and Effects of Oocyte Retrieval Difficulties: A Retrospective Study of 10,624 Cycles.取卵困难的原因及后果:10624 个周期的回顾性研究。
Front Endocrinol (Lausanne). 2022 Jan 3;12:564344. doi: 10.3389/fendo.2021.564344. eCollection 2021.
5
Evaluation of follicular flushing with double lumen needle in patients undergoing assisted reproductive technology treatments.评估在接受辅助生殖技术治疗的患者中使用双腔管针进行卵泡冲洗。
JBRA Assist Reprod. 2021 Apr 27;25(2):272-275. doi: 10.5935/1518-0557.20210009.
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Follicular flushing during oocyte retrieval in assisted reproductive techniques.辅助生殖技术中取卵时的卵泡冲洗
Cochrane Database Syst Rev. 2018 Apr 26;4(4):CD004634. doi: 10.1002/14651858.CD004634.pub3.
7
Randomized, open trial comparing a modified double-lumen needle follicular flushing system with a single-lumen aspiration needle in IVF patients with poor ovarian response.随机、开放试验比较了改良型双腔针卵泡冲洗系统与单腔抽吸针在卵巢反应不良的 IVF 患者中的应用。
Hum Reprod. 2017 Apr 1;32(4):832-835. doi: 10.1093/humrep/dex019.
8
Approaches to oocyte retrieval for advanced reproductive technology cycles planning to utilize in vitro maturation: a review of the many choices to be made.用于计划采用体外成熟技术的辅助生殖技术周期的卵母细胞采集方法:对众多决策选择的综述
J Assist Reprod Genet. 2014 Nov;31(11):1409-19. doi: 10.1007/s10815-014-0334-9. Epub 2014 Sep 12.
9
Comparison of complication rates and pain scores after transvaginal ultrasound-guided oocyte pickup procedures for in vitro maturation and in vitro fertilization cycles.经阴道超声引导下取卵术在体外成熟和体外受精周期中并发症发生率和疼痛评分的比较。
Fertil Steril. 2014 Mar;101(3):705-9. doi: 10.1016/j.fertnstert.2013.12.011. Epub 2014 Jan 11.
10
Correlation between follicular diameters and flushing versus no flushing on oocyte maturity, fertilization rate and embryo quality.卵泡直径与卵母细胞成熟时是否出现黄素化/无黄素化、受精率和胚胎质量的相关性。
J Assist Reprod Genet. 2014 Jan;31(1):73-7. doi: 10.1007/s10815-013-0124-9. Epub 2013 Nov 6.