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扁桃体切除术对腭扁桃体炎和腭扁桃体肥大患者生活质量的长期影响

Long-Term Impact of Tonsillectomy on Quality of Life (QoL) in Patients with Palatine Tonsillitis and Palatine Tonsillar Hypertrophy.

作者信息

Jurkiewicz Aleksander, Bant Przemysław, Szczygielski Kornel, Kaczmarczyk Michał, Jurkiewicz Dariusz

机构信息

Department of Otolaryngology and Oncological Laryngology with Cranio-Maxillofacial Surgery Unit, Military Institute of Medicine-National Research Institute, 04-141 Warsaw, Poland.

出版信息

J Clin Med. 2025 Sep 10;14(18):6404. doi: 10.3390/jcm14186404.

DOI:10.3390/jcm14186404
PMID:41010609
Abstract

Tonsillectomy is one of the most common surgical procedures and, given the limited efficacy of conservative treatment, remains the primary approach for managing palatine tonsillitis (PT) and palatine tonsillar hypertrophy (PTH). Both conditions negatively affect quality of life (QoL), increase healthcare costs, and contribute to work absenteeism. The primary aim of this study is to assess QoL following tonsillectomy and uvulopalatopharyngoplasty (UPPP) in patients qualified for surgical treatment due to PT and PTH. A prospective cohort study was conducted among 89 adults (85% follow-up) who had undergone tonsillectomy and UPPP. QoL was assessed 6 years post-op using the Glasgow Benefit Inventory (GBI), the Schwentner questionnaire, and VAS. The study group included 89 patients (85% of those who underwent surgery), including 26 women (29%) and 63 men (71%). Patients with PT and PTH showed significant QoL improvement after palatine tonsillectomy. The mean GBI score indicated QoL improvement after both tonsillectomy (+25.7) and UPPP (+15.8), with the most pronounced improvements in physical and general health. Overall, GBI scores were higher in PT compared to PTH (26.6 compared to 15.5), mainly due to better results in the physical health domain (55.9 compared to 12.9). Palatine tonsillectomy has a positive impact on QoL in both PT and PTH patients, with higher questionnaire scores observed in the PT group. Tonsillectomy contributed more significantly to the improvement in QoL than UPPP, as measured by the GBI, the Schwentner questionnaire, and the Visual Analogue Scale (VAS). Furthermore, our study demonstrated that, when evaluating and qualifying patients for tonsillectomy, a more comprehensive otolaryngological assessment should be conducted, including evaluation of the nasal cavity and nasopharynx, as comorbid conditions in these regions are correlated with postoperative QoL outcomes.

摘要

扁桃体切除术是最常见的外科手术之一,鉴于保守治疗效果有限,它仍是治疗腭扁桃体炎(PT)和腭扁桃体肥大(PTH)的主要方法。这两种病症均对生活质量(QoL)产生负面影响,增加医疗成本,并导致旷工。本研究的主要目的是评估因PT和PTH而有资格接受手术治疗的患者在扁桃体切除术后和悬雍垂腭咽成形术(UPPP)后的生活质量。对89名接受过扁桃体切除术和UPPP的成年人进行了一项前瞻性队列研究(随访率85%)。术后6年使用格拉斯哥效益量表(GBI)、施温特纳问卷和视觉模拟量表(VAS)评估生活质量。研究组包括89名患者(占接受手术患者的85%),其中26名女性(29%),63名男性(71%)。PT和PTH患者在腭扁桃体切除术后生活质量有显著改善。GBI平均得分表明扁桃体切除术(+25.7)和UPPP(+15.8)后生活质量均有改善,身体和总体健康方面改善最为明显。总体而言,PT患者的GBI得分高于PTH患者(分别为26.6和15.5),主要是因为身体健康领域的结果更好(分别为55.9和12.9)。腭扁桃体切除术对PT和PTH患者的生活质量均有积极影响,PT组的问卷得分更高。通过GBI、施温特纳问卷和视觉模拟量表(VAS)测量,扁桃体切除术对生活质量改善的贡献比UPPP更显著。此外,我们的研究表明,在评估患者是否适合进行扁桃体切除术时,应进行更全面的耳鼻喉科评估,包括鼻腔和鼻咽的评估,因为这些区域的合并症与术后生活质量结果相关。

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本文引用的文献

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Selected Immunohistochemical Assessment and Clinical Examinations in the Diagnosis of Palatine Tonsil Diseases.腭扁桃体疾病诊断中的免疫组织化学评估与临床检查
J Clin Med. 2023 Jul 6;12(13):4522. doi: 10.3390/jcm12134522.
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Quality of Life Postchronic Tonsillitis Treatments: An Original Research.慢性扁桃体炎治疗后的生活质量:一项原创研究。
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Quality of life after tonsillectomy in adult patients with recurrent acute tonsillitis: a systematic review.
成人复发性急性扁桃体炎患者扁桃体切除术后的生活质量:系统评价。
Eur Arch Otorhinolaryngol. 2022 Jun;279(6):2753-2764. doi: 10.1007/s00405-022-07260-7. Epub 2022 Jan 19.
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Patient Perspectives on Removing Adult Tonsillectomy and Septoplasty from the Government Health Insurance Plan in a Publicly Funded Health Care System.在公费医疗保健系统中,从政府医保计划中移除成人扁桃体切除术和鼻中隔成形术的患者观点。
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Nasal Obstruction and Quality of Life Assessment After Septoplasty With Turbinoplasty: Correlation Between Subjective Scales.鼻中隔偏曲矫正术后伴鼻甲成形术患者的鼻腔阻塞及生活质量评估:主观量表间的相关性。
Am J Rhinol Allergy. 2021 Sep;35(5):568-573. doi: 10.1177/1945892420978956. Epub 2020 Dec 9.
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Qual Life Res. 2019 Oct;28(10):2641-2650. doi: 10.1007/s11136-019-02214-9. Epub 2019 Jun 11.
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AMIA Annu Symp Proc. 2018 Apr 16;2017:1169-1178. eCollection 2017.
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The effect of tonsillectomy on the morbidity from recurrent tonsillitis.扁桃体切除术对复发性扁桃体炎发病率的影响。
Clin Otolaryngol. 2017 Dec;42(6):1206-1210. doi: 10.1111/coa.12850. Epub 2017 Mar 9.
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Clin Otolaryngol. 2016 Jun;41(3):259-75. doi: 10.1111/coa.12518. Epub 2016 Feb 7.
10
Does tonsillectomy improve quality of life in adults? A systematic literature review.扁桃体切除术能改善成年人的生活质量吗?一项系统的文献综述。
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