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吲哚菁绿血管造影术在血栓闭塞性脉管炎所致动脉溃疡患者手术截肢平面评估中的应用

Indocyanine Green Angiography in the Evaluation of Surgical Amputation Level in Patients with Arterial Ulcers Due to Thromboangiitis Obliterans.

作者信息

Akyüz Simay, Güven Hikmet Erhan, Yılmaz Kerim Bora

机构信息

Department of Oncology Nursing, Gulhane Faculty of Nursing, University of Health Sciences, Ankara 06010, Turkey.

Department of General Surgery, Diabetic Foot and Chronic Wounds, University of Health Sciences, Etlik City Hospital, Ankara 06010, Turkey.

出版信息

Medicina (Kaunas). 2025 Sep 16;61(9):1678. doi: 10.3390/medicina61091678.

Abstract

: The aim of this study was to evaluate the role of Indocyanine Green Angiography (ICGA) on amputation levels and the wound healing process in patients with thromboangiitis obliterans (TAO) and complex diabetes. : The research was conducted on 26 inpatients, with TAO and lower extremity ulcers, who were treated between November 2019 and September 2021. A retrospective analysis was made of overall health status, wound characteristics, and surgical outcomes. : The patients comprised 88.5% males and 11.5% females, with a mean age of 62.31 years. In 84.6% of the patients evaluated with ICG angiography, the wound healing process was achieved with no complications. Negative and positive correlations were identified between ICG density values and wound healing time, disease-free follow-up time, and ICG full density time. : These findings suggest that ICG angiography may assist in achieving safe surgical margins for patients with TAO. In conclusion, ICG angiography can be considered a valuable predictive tool for assessing tissue perfusion in TAO-related lower extremity ulcers.

摘要

本研究旨在评估吲哚菁绿血管造影(ICGA)在血栓闭塞性脉管炎(TAO)合并复杂性糖尿病患者截肢平面及伤口愈合过程中的作用。本研究对2019年11月至2021年9月期间接受治疗的26例患有TAO和下肢溃疡的住院患者进行。对总体健康状况、伤口特征和手术结果进行了回顾性分析。患者中男性占88.5%,女性占11.5%,平均年龄为62.31岁。在84.6%接受ICG血管造影评估的患者中,伤口愈合过程顺利,无并发症。ICG密度值与伤口愈合时间、无病随访时间及ICG全密度时间之间存在负相关和正相关。这些发现表明,ICGA可能有助于为TAO患者实现安全的手术切缘。总之,ICGA可被视为评估TAO相关下肢溃疡组织灌注的有价值的预测工具。

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