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2型糖尿病成人患者饮食失调的患病率及相关因素:一项系统综述

Prevalence and associated factors of eating disorders in adults with type 2 diabetes: a systematic review.

作者信息

Celik Esmer Aycan, Jalal Zahraa, Guo Ping, Seckin Muzeyyen

机构信息

Faculty of Health Sciences, Internal Medicine Nursing Department, Uşak University, Uşak, Turkey.

Department of Pharmacy, School of Pharmacy, School of Health Sciences, College of Medicine and Health, University of Birmingham, Birmingham, UK.

出版信息

J Eat Disord. 2025 Sep 26;13(1):211. doi: 10.1186/s40337-025-01391-y.

Abstract

BACKGROUND

People with type 2 diabetes (T2DM) have a higher risk of eating disorders, specifically binge eating disorders (BED) and night eating syndrome (NES) which may affect the diabetes management and long-term outcomes of T2DM. There is limited evidence to determine the prevalence and associated factors of this condition for targeted interventions. Our study aimed to systematically synthesise existing evidence exploring the prevalence of eating disorders and associated factors among adults with T2DM.

METHODS

This review was pre-registered with PROSPERO (CRD42024587276). A systematic review was undertaken searching Embase, Medline, PsycINFO, Cochrane Central database. The National Institutes of Health Quality Assessment tool for Observational Cohort and Cross-Sectional Studies was used to evaluate the quality of eligible studies. Given the insufficient number of studies assessing the targeted outcomes, a meta-analysis was not attempted. A narrative synthesis was conducted.

RESULTS

Twelve studies were included with cross-sectional studies. BED and NES were the two most common eating disorders in people with T2DM. Point prevalence was 2.5-29.6% for BED and 1.6-8.4% for NES. No data were available on the prevalence of bulimia and anorexia nervosa. Having eating disorders in T2DM was associated with a low level of psychological well-being, greater depression, anxiety symptoms, and high levels of BMI and HbA1c.

CONCLUSION

There are psychological, physical and social factors associated with to high prevalence of eating disorders in T2DM. The current literature on eating disorders in T2DM is relatively limited, with few studies applying rigorous methods. Further studies are needed for large, high-quality studies that focus on the management, diagnosis, physical and psychosocial effects, and long-term outcomes of eating disorders in adults with T2DM.

摘要

背景

2型糖尿病(T2DM)患者患饮食失调症的风险更高,尤其是暴饮暴食症(BED)和夜间进食综合征(NES),这可能会影响糖尿病的管理以及T2DM的长期预后。目前确定该病症患病率及相关因素以进行针对性干预的证据有限。我们的研究旨在系统地综合现有证据,探讨T2DM成年患者饮食失调症的患病率及相关因素。

方法

本综述已在国际前瞻性系统评价注册库(PROSPERO,注册号:CRD42024587276)进行预注册。通过检索Embase、Medline、PsycINFO、Cochrane Central数据库进行系统综述。使用美国国立卫生研究院观察性队列研究和横断面研究质量评估工具来评估纳入研究的质量。鉴于评估目标结局的研究数量不足,未进行荟萃分析,而是进行了叙述性综合分析。

结果

纳入了12项横断面研究。BED和NES是T2DM患者中最常见的两种饮食失调症。BED的时点患病率为2.5%-29.6%,NES为1.6%-8.4%。未获得有关贪食症和神经性厌食症患病率的数据。T2DM患者患有饮食失调症与心理健康水平低、抑郁和焦虑症状更严重以及BMI和糖化血红蛋白(HbA1c)水平高有关。

结论

T2DM患者饮食失调症患病率高与心理、身体和社会因素有关。目前关于T2DM患者饮食失调症的文献相对有限,采用严格方法的研究较少。需要进一步开展大型高质量研究,关注T2DM成年患者饮食失调症的管理、诊断、身体和心理社会影响以及长期预后。

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