Paudex Théo, Endomba Francky Teddy, Forestier Nathalie, Pierandrei Achille, Chauvet-Gélinier Jean-Christophe, Pinoit Jean-Michel
Université Bourgogne Europe, Dijon, France.
PADYS Research Group, INSERM Research Center U1231, Dijon, France.
Clin Psychol Psychother. 2025 Sep-Oct;32(5):e70150. doi: 10.1002/cpp.70150.
The aim of the study was to estimate the prevalence of eating disorders (EDs) across the borderline personality disorder (BPD) population.
After protocol registration (number = CRD42023415721), we systematically searched PubMed/MEDLINE, PsycINFO and Web of Science for articles that allowed the assessment of the proportion of at least one ED in a sample of patients with BPD. Risk of bias was estimated using the Joanna Briggs Institute (JBI) checklist for studies reporting prevalence data, and we used a random-effects meta-analytic model. We used the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA 2020) statement.
A total of 34 articles were included, with 20 reports (N = 4107) related to EDs without distinction, and 20 (n = 3901), 20 (n = 4369), seven (n = 766), and six (n = 1773) reports related to anorexia nervosa (AN), bulimia nervosa (BN), binge eating disorder (BED), and eating disorder not otherwise specified (EDNOS), respectively. The overall frequency of EDs in BPD was estimated to be 29.7% (95% CI = [21.6%, 38.4%]), while the frequencies of AN, BN, BED, and EDNOS were estimated to be 9.98% (95% CI = [5.6%, 15.3%]), 16.3% (95% CI = [12.1%, 21.1%]), 16.3% (95% CI = [6%, 30%]) and 18.8% (95% CI = [10.6%, 28.6%]), respectively. The overall risk of bias was moderate, there was no publication bias, and the certainty levels of our evidence were low.
This meta-analytic review highlights the high frequency of EDs in BPD. It could serve as a basis for exploring the determinants of these comorbidities.
Through this systematic review and meta-analysis, we found a high prevalence of EDs and their subtypes in patients with BPD.
本研究旨在评估边缘型人格障碍（BPD）人群中饮食失调（EDs）的患病率。
在方案注册（编号 = CRD42023415721）后，我们系统地检索了PubMed/MEDLINE、PsycINFO和Web of Science，以查找能够评估BPD患者样本中至少一种EDs比例的文章。使用乔安娜·布里格斯研究所（JBI）报告患病率数据的研究清单来估计偏倚风险，我们采用随机效应荟萃分析模型。我们遵循系统评价和荟萃分析的首选报告项目（PRISMA 2020）声明。
共纳入34篇文章，其中20篇报告（N = 4107）与未区分的EDs相关，20篇（n = 3901）、20篇（n = 4369）、7篇（n = 766）和6篇（n = 1773）报告分别与神经性厌食症（AN）、神经性贪食症（BN）、暴饮暴食症（BED）和未另行规定的饮食失调（EDNOS）相关。BPD中EDs的总体发生率估计为29.7%（95%置信区间 = [21.6%，38.4%]），而AN、BN、BED和EDNOS的发生率估计分别为9.98%（95%置信区间 = [5.6%，15.3%]）、16.3%（95%置信区间 = [12.1%，21.1%]）、16.3%（95%置信区间 = [6%，30%]）和18.8%（95%置信区间 = [10.6%，28.6%]）。总体偏倚风险为中度，不存在发表偏倚，我们证据的确定性水平较低。
这项荟萃分析综述突出了BPD中EDs的高发生率。它可以作为探索这些共病决定因素的基础。
通过这项系统评价和荟萃分析，我们发现BPD患者中EDs及其亚型的患病率很高。
