Ma Lin, Zhang Hao, Yan Shuo, Bai Weixing, Zhang Yingqiang, Wu Dedi, Du Jiahang, Lu Zhiyong, Tan Huaqiao
Department of Interventional Radiology, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, China.
Department of Interventional Radiology, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China.
Front Neurol. 2025 Sep 11;16:1650169. doi: 10.3389/fneur.2025.1650169. eCollection 2025.
Endovascular recanalization treatment (EVRT) has emerged as a critical treatment modality for patients with symptomatic atherosclerotic non-acute middle cerebral artery occlusion (SNMCAO). However, several technical challenges persist, and the predictive factors for successful recanalization of SNMCAO are not yet fully understood. This study aimed to identify clinical and radiological factors associated with successful EVRT in patients with SNMCAO.
We conducted a retrospective analysis on all patients with SNMCAO who underwent EVRT at two centers from January 2016 to December 2024. Demographic data, medical history, imaging characteristics, periprocedural complications, and 3-month follow-up results were collected. Logistic binary regression analysis was performed to assess the factors influencing the success of EVRT.
A total of 65 patients were included, with 50 achieving successful recanalization. The perioperative complication rate was 13.8% (9/65). Multivariate logistic binary regression analysis indicated that an occlusion duration of ≤ 3 months ( = 0.020), an occlusion segment length of ≤ 10 mm ( = 0.004), the presence of a distal vascular main trunk visualization (DVMTV) sign ( = 0.035), and the presence of a slow distal antegrade flow (SDFA) sign ( = 0.039) were identified as independent positive predictors of successful EVRT for SNMCAO.
Occlusion duration of ≤ 3 months, occlusion length of ≤ 10 mm, the presence of a DVMTV sign and a SDFA sign were considered independent predictive factors for the success of EVRT in patients with SNMCAO.
血管内再通治疗（EVRT）已成为有症状的动脉粥样硬化性非急性大脑中动脉闭塞（SNMCAO）患者的关键治疗方式。然而，仍存在一些技术挑战，且SNMCAO成功再通的预测因素尚未完全明确。本研究旨在确定与SNMCAO患者EVRT成功相关的临床和影像学因素。
我们对2016年1月至2024年12月在两个中心接受EVRT的所有SNMCAO患者进行了回顾性分析。收集了人口统计学数据、病史、影像学特征、围手术期并发症及3个月随访结果。进行逻辑二元回归分析以评估影响EVRT成功的因素。
共纳入65例患者，其中50例成功再通。围手术期并发症发生率为13.8%（9/65）。多因素逻辑二元回归分析表明，闭塞持续时间≤3个月（P = 0.020）、闭塞节段长度≤10 mm（P = 0.004）、存在远端血管主干显影（DVMTV）征（P = 0.035）及存在缓慢的远端正向血流（SDFA）征（P = 0.039）被确定为SNMCAO患者EVRT成功的独立阳性预测因素。
闭塞持续时间≤3个月、闭塞长度≤10 mm、存在DVMTV征和SDFA征被认为是SNMCAO患者EVRT成功的独立预测因素。
