Ameni Gobena, Zewude Aboma, Bayissa Berecha, Albizreh Abdallah A, Alhosani Naeema, Alkalbani Meera Saeed, Abdelhalim Mohamed Moustafa, Abdelazim Assem Sobhi, Koliyan Rafeek Aroul, Kayaf Kaltham, Nuaimat Mervat Mari Al, Barigye Robert, Ádám Balázs, Sheek-Hussein Mohamud, Zhang Guangzhi, Eltahir Yassir Mohammed, Tibbo Markos
Department of Veterinary Medicine, College of Agriculture and Veterinary Medicine, United Arab Emirates University, Al Ain, Abu Dhabi, UAE.
Vaccine Production and Drug Formulation Directorate, National Veterinary Institute, Debre Zeit, Ethiopia.
Transbound Emerg Dis. 2025 Sep 19;2025:7748638. doi: 10.1155/tbed/7748638. eCollection 2025.
Brucellosis remains a critical zoonotic disease affecting livestock productivity and human health, especially in regions where intensive livestock husbandry is practiced. In the United Arab Emirates (UAE), camels contribute economically and culturally through meat, milk, and racing, yet data on brucellosis in camels and its zoonotic risk remain limited. This cross-sectional study aimed to determine the seroprevalence and molecular detection of species in camels and abattoir workers in the Emirate of Abu Dhabi, UAE. A total of 356 camels from 102 herds, 368 slaughter camels, and 86 abattoir workers were included. Competitive enzyme-linked immunosorbent assay (cELISA) was used for antibody detection, while species-specific quantitative PCR (qPCR) targeted , , and in seropositive samples. Herd-level seroprevalence was 10.8% (95% CI: 5.5%-18.5%) and significantly associated with herd size ( < 0.05). Animal seroprevalence was 5.9% (95% confidence level [CI]: 3.7%-8.9%) in field camels and 3.0% (95% CI: 1.51%-5.30%) in slaughtered camels. Seven abattoir workers (8.1%) were seropositive, with butchers at greater risk. By species, , and were detected in camels, while only and were in abattoir workers. These findings indicate ongoing zoonotic risks in abattoir settings and support integrated One Health surveillance and control strategies.
布鲁氏菌病仍然是一种严重的人畜共患病，影响着牲畜生产力和人类健康，尤其是在实行集约化畜牧业的地区。在阿拉伯联合酋长国（阿联酋），骆驼在经济和文化方面通过肉、奶和赛跑做出贡献，但关于骆驼布鲁氏菌病及其人畜共患病风险的数据仍然有限。这项横断面研究旨在确定阿联酋阿布扎比酋长国骆驼和屠宰场工人中布鲁氏菌的血清阳性率和分子检测情况。共纳入了来自102个畜群的356头骆驼、368头屠宰骆驼和86名屠宰场工人。采用竞争酶联免疫吸附测定（cELISA）进行抗体检测，而针对血清阳性样本中的布鲁氏菌属、流产布鲁氏菌和马尔他布鲁氏菌进行种特异性定量聚合酶链反应（qPCR）。畜群水平的血清阳性率为10.8%（95%置信区间：5.5%-18.5%），且与畜群规模显著相关（P<0.05）。野外骆驼的动物血清阳性率为5.9%（95%置信水平[CI]：3.7%-8.9%），屠宰骆驼的血清阳性率为3.0%（95%CI：1.51%-5.30%）。七名屠宰场工人（8.1%）血清呈阳性，屠夫的风险更高。按种分类，在骆驼中检测到羊种布鲁氏菌、牛种布鲁氏菌和马尔他布鲁氏菌，而在屠宰场工人中仅检测到羊种布鲁氏菌和马尔他布鲁氏菌。这些发现表明屠宰场环境中存在持续的人畜共患病风险，并支持综合的“同一个健康”监测和控制策略。
