Douami Anas, Labied Mohamed, Mountassir Chorouk, Lembarki Ghizlane, Sabiri Mouna, Lezar Samira
Central Radiology Department - Center Hospitalier IBN ROCHD - Faculty of Medicine and Pharmacy of Casablanca, Hassan II University, Casablanca, Morocco.
Radiol Case Rep. 2025 Sep 15;20(12):5968-5973. doi: 10.1016/j.radcr.2025.08.019. eCollection 2025 Dec.
Metastatic pulmonary calcification (MPC), also known as pulmonary calcinosis, is a metabolic lung disease characterized by the deposition of calcium in lung tissue due to hypercalcemia. MPC is often a long-term complication of chronic renal failure. The pathological process is marked by the interstitial deposition of calcium salts, primarily within the alveolar epithelial basement membranes. Although histological changes indicative of MPC are observed in 60%-75% of hemodialysis patients at autopsy, it is infrequently diagnosed before death. While the condition is typically asymptomatic, it can progress to respiratory failure in some cases. Computed tomography (CT) has been shown to be more sensitive than conventional radiography in detecting MPC, with the most common CT finding being multiple calcified pulmonary nodules. We present a case of metastatic pulmonary calcification in a 50-year-old male patient undergoing treatment for chronic renal failure.
转移性肺钙化（MPC），也称为肺钙质沉着症，是一种代谢性肺部疾病，其特征是由于高钙血症导致钙在肺组织中沉积。MPC通常是慢性肾衰竭的长期并发症。病理过程的特点是钙盐在间质沉积，主要在肺泡上皮基底膜内。尽管在尸检中60%-75%的血液透析患者观察到了提示MPC的组织学变化，但在死亡前很少被诊断出来。虽然这种情况通常无症状，但在某些情况下可进展为呼吸衰竭。计算机断层扫描（CT）已被证明在检测MPC方面比传统放射学更敏感，最常见的CT表现是多个钙化的肺结节。我们报告一例50岁男性慢性肾衰竭患者发生转移性肺钙化的病例。
