Suppr超能文献

梅克尔憩室致成人大量胃肠道出血:一例报告

Massive Gastrointestinal Hemorrhage in an Adult Caused by Meckel's Diverticulum: A Case Report.

作者信息

Zheng Ludan, Li Liangliang, Huo Yubin, Su Hui

机构信息

General Surgery Department, Ningbo No. 2 Hospital, Ningbo, Zhejiang, People's Republic of China.

General Surgery Department, Haishu People's Hospital, Ningbo, Zhejiang, People's Republic of China.

出版信息

Int Med Case Rep J. 2025 Sep 26;18:1253-1259. doi: 10.2147/IMCRJ.S541384. eCollection 2025.

Abstract

Meckel's diverticulum is one of the most common congenital anomalies of the gastrointestinal tract in pediatric populations worldwide. Although Meckel's diverticulum itself is usually asymptomatic, patients often present with complications such as gastrointestinal bleeding, Meckel's diverticulitis, intestinal perforation, and other associated symptoms. Notably, Meckel's diverticulum is relatively uncommon in adults, with cases complicated by acute massive gastrointestinal bleeding being particularly rare. We report the case of a 41-year-old man presenting with hematochezia for one day. Upon admission, his hemoglobin level dropped significantly from 98 g/L to 62 g/L within 24 hours. Contrast-enhanced computed tomography strongly suggested contrast media extravasation, indicating active bleeding. Subsequent gastrointestinal endoscopy, including colonoscopy, failed to identify obvious pathological findings. Mesenteric angiography successfully localized the bleeding vessels, but multiple embolization attempts were unsuccessful. The initial imaging and endoscopic modalities may not pinpoint the source of bleeding in this rare condition. Ultimately, a combined laparoscopic and endoscopic approach was employed, which successfully identified and localized the bleeding site in the Meckel's diverticulum. Laparoscopic intestinal resection was then performed, and postoperative pathological examination confirmed Meckel's diverticulum with ectopic gastric tissue. Meckel's diverticulum-induced bleeding in adults is severe yet rare, with nonspecific diagnostic features that often complicate timely identification. In managing the case of massive gastrointestinal hemorrhage, we achieved a successful outcome through combined laparoscopic intestinal resection and endoscopic surgery, with timely diagnosis and targeted intervention leading to complete recovery. This case underscores the critical role of a multimodal diagnostic and therapeutic strategy, particularly the integration of laparoscopy and endoscopy, in overcoming the challenges of nonspecific presentations. It serves as a valuable reference for clinicians, emphasizing that persistent diagnostic uncertainty in severe lower gastrointestinal bleeding should prompt consideration of rare etiologies like Meckel's diverticulum, and that a combined surgical-endoscopic approach can be pivotal in achieving definitive diagnosis and curative treatment.

摘要

梅克尔憩室是全球儿科人群中最常见的胃肠道先天性异常之一。虽然梅克尔憩室本身通常无症状,但患者常出现胃肠道出血、梅克尔憩室炎、肠穿孔等并发症及其他相关症状。值得注意的是,梅克尔憩室在成人中相对少见,并发急性大量胃肠道出血的病例尤为罕见。我们报告一例41岁男性,便血1天。入院时,他的血红蛋白水平在24小时内从98 g/L显著降至62 g/L。增强CT强烈提示造影剂外渗,表明存在活动性出血。随后的包括结肠镜检查在内的胃肠道内镜检查未能发现明显的病理结果。肠系膜血管造影成功定位了出血血管,但多次栓塞尝试均未成功。在这种罕见情况下,最初的影像学和内镜检查方法可能无法确定出血来源。最终,采用了腹腔镜和内镜联合方法,成功识别并定位了梅克尔憩室内的出血部位。然后进行了腹腔镜肠切除术,术后病理检查证实为梅克尔憩室伴异位胃组织。成人梅克尔憩室引起的出血严重但罕见,其诊断特征不具特异性,常使及时识别复杂化。在处理大量胃肠道出血病例时,我们通过腹腔镜肠切除术和内镜手术联合治疗取得了成功结果,及时诊断和针对性干预使患者完全康复。该病例强调了多模式诊断和治疗策略的关键作用,特别是腹腔镜和内镜的结合,以克服非特异性表现带来的挑战。它为临床医生提供了有价值的参考,强调在严重下消化道出血中持续存在的诊断不确定性应促使考虑梅克尔憩室等罕见病因,并且联合手术 - 内镜方法对于实现明确诊断和根治性治疗可能至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/281f/12482944/78d195a24172/IMCRJ-18-1253-g0001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验