青霉素酶质粒在金黄色葡萄球菌中的稳定性。
Stability of penicillinase plasmids in Staphylococcus aureus.
作者信息
Johnston L H, Dyke K G
出版信息
J Bacteriol. 1971 Jul;107(1):68-73. doi: 10.1128/jb.107.1.68-73.1971.
Abstract
The isolation of mutants of Staphylococcus aureus that are affected in the stability of penicillinase plasmids is described. One mutation is plasmid borne and results in nonreplication of the plasmid at 42 C. A second type of mutation is host-borne and gives rise to instability of both mcr(I) and mcr(II) penicillinase plasmids but not a tetracycline-resistant plasmid.
摘要
本文描述了金黄色葡萄球菌突变体的分离情况，这些突变体在青霉素酶质粒稳定性方面受到影响。一种突变由质粒携带，导致质粒在42℃时不复制。第二种突变类型由宿主携带，会导致mcr(I)和mcr(II)青霉素酶质粒不稳定，但不会导致四环素抗性质粒不稳定。
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