“医院”葡萄球菌中各种类型青霉素酶质粒的出现情况。
Occurrence of various types of penicillinase plasmid among 'hospital' staphylococci.
作者信息
Dyke K G, Richmond M H
出版信息
J Clin Pathol. 1967 Jan;20(1):75-9. doi: 10.1136/jcp.20.1.75.
Abstract
The type of penicillinase plasmid carried by penicillin-resistant cultures of Staphylococcus aureus isolated from eight London hospitals has been determined. Among ;endemic' hospital staphylococci, cultures resistant to mercury salts and producing large amounts of A-type penicillinase, a high proportion of which is extracellular, are most common. C-type penicillinase is rarely associated with resistance to mercury salts.The majority of strains resistant to penicillin and at least one other antibiotic carried the alpha-plasmid. Possible reasons for the prevalence of the alpha-plasmid among endemic hospital staphylococci are discussed.
摘要
已确定从伦敦八家医院分离出的耐青霉素金黄色葡萄球菌培养物所携带的青霉素酶质粒类型。在“地方性”医院葡萄球菌中，对汞盐耐药并产生大量A型青霉素酶（其中很大一部分是细胞外酶）的培养物最为常见。C型青霉素酶很少与对汞盐的耐药性相关。大多数对青霉素和至少一种其他抗生素耐药的菌株携带α质粒。文中讨论了α质粒在地方性医院葡萄球菌中普遍存在的可能原因。
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