Sonstein S A, Baldwin J N
J Bacteriol. 1972 Jan;109(1):262-5. doi: 10.1128/jb.109.1.262-265.1972.
Two strains of Staphylococcus aureus (PC1 and 196E), when grown in medium containing 0.002% sodium dodecyl sulfate (SDS), showed from 96.1 to 100% loss of the ability to produce penicillinase. Resistance to cadmium and zinc was lost concomitantly with the ability to produce penicillinase. A comparison of the rate of curing by SDS with the curing effects exerted by elevated temperature and ethidium bromide suggested that SDS is a more effective plasmid curing agent for susceptible strains of S. aureus than methods in use at present.
两株金黄色葡萄球菌(PC1和196E)在含有0.002%十二烷基硫酸钠(SDS)的培养基中生长时,产生青霉素酶的能力丧失了96.1%至100%。对镉和锌的抗性与产生青霉素酶的能力同时丧失。将SDS的消除速率与高温和溴化乙锭所产生的消除效果进行比较表明,对于金黄色葡萄球菌的敏感菌株,SDS是一种比目前使用的方法更有效的质粒消除剂。