[Action of sustained release nitroglycerin on a pulmonary artery pressure in coronary heart disease (author's transl)].

In 12 patients with coronary heart disease and increased left ventricular filling pressure the pressure lowering effect of an oral long-acting nitroglycerin preparation (Sustac-Retard forte) was investigated at rest (n = 6) and during exercise (n = 6). The systolic and end-diastolic pulmonary artery pressure decreased significantly for up to 6 hours after the ingestion of 6.5 mg of nitroglycerin. The most marked pressure changes in the pulmonary circulation occurred 2 to 4 hours after ingestion of the tablets. All patients noticed reduction of dyspnoea and (or) anginal pain.