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胎儿心脏肿块。

Fetal cardiac masses.

作者信息

Rathore Bhagyashree, Adamson Marissa E, Berklite Lara E, Debnath Pradipta, Kline-Fath Beth M, Miles Kimberley G, Morin Cara E, Schneider Kristin A

机构信息

Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH, 45229, USA.

University of Cincinnati Medical Center, Cincinnati, USA.

出版信息

Pediatr Radiol. 2025 Oct 22. doi: 10.1007/s00247-025-06431-y.

DOI:10.1007/s00247-025-06431-y
PMID:41123646
Abstract

Although rare in the pediatric population, cardiac tumors represent a significant portion of prenatally detected masses, second only to sacrococcygeal teratomas. Fetal cardiac masses are predominantly benign, with rhabdomyoma being the most common fetal cardiac mass in the setting of tuberous sclerosis. Multiple lesions are pathognomonic for rhabdomyomas and prompt evaluation for tuberous sclerosis. Fibroma, teratoma, and hemangioma are other consistently detected cardiac tumors. In this article, we review the epidemiology, imaging, treatment, and outcomes of these fetal cardiac masses, emphasizing the role of imaging in surveillance, identifying complications, refining the differential diagnosis, and recognizing potential diagnostic pitfalls.

摘要

尽管心脏肿瘤在儿科人群中较为罕见,但却是产前检测到的肿块的重要组成部分,仅次于骶尾部畸胎瘤。胎儿心脏肿块大多为良性,横纹肌瘤是结节性硬化症背景下最常见的胎儿心脏肿块。多个病灶是横纹肌瘤的特征性表现,提示需对结节性硬化症进行及时评估。纤维瘤、畸胎瘤和血管瘤是其他经常检测到的心脏肿瘤。在本文中,我们回顾了这些胎儿心脏肿块的流行病学、影像学、治疗及预后情况,重点强调了影像学在监测、识别并发症、完善鉴别诊断及认识潜在诊断陷阱方面的作用。

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1
Fetal cardiac masses.胎儿心脏肿块。
Pediatr Radiol. 2025 Oct 22. doi: 10.1007/s00247-025-06431-y.
2
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本文引用的文献

1
Prenatally Diagnosed Cardiac Tumors and Tuberous Sclerosis Complex: A Single-Center Experience.产前诊断的心脏肿瘤与结节性硬化症复合体:单中心经验
Children (Basel). 2025 Jan 16;12(1):94. doi: 10.3390/children12010094.
2
Fetal Safety in MRI During Pregnancy: A Comprehensive Review.孕期磁共振成像中的胎儿安全性:全面综述
Diagnostics (Basel). 2025 Jan 17;15(2):208. doi: 10.3390/diagnostics15020208.
3
Transplacental Sirolimus for Reversal of Fetal Heart Failure due to Fetal Cardiac Rhabdomyoma: Fetal and Maternal Considerations.
经胎盘使用西罗莫司逆转胎儿心脏横纹肌瘤所致胎儿心力衰竭:胎儿及母体相关考量
Fetal Diagn Ther. 2025;52(4):420-428. doi: 10.1159/000542664. Epub 2025 Jan 22.
4
Mediastinal Teratoma in a Twin Pregnancy: A Case Report.双胎妊娠合并纵隔畸胎瘤:一例报告
Cureus. 2024 Nov 5;16(11):e73074. doi: 10.7759/cureus.73074. eCollection 2024 Nov.
5
Type and dimensions can predict ventricular arrhythmias and cardiac death in primary benign cardiac tumors in children.类型和大小可预测儿童原发性良性心脏肿瘤中的室性心律失常和心脏性死亡。
Int J Cardiol. 2025 Jan 1;418:132599. doi: 10.1016/j.ijcard.2024.132599. Epub 2024 Sep 24.
6
Fetal Cardiac MRI Using Doppler US Gating: Emerging Technology and Clinical Implications.胎儿心脏 MRI 采用超声门控多普勒技术:新兴技术与临床应用。
Radiol Cardiothorac Imaging. 2024 Apr;6(2):e230182. doi: 10.1148/ryct.230182.
7
Postmortem 7T MRI in Goltz-Gorlin Syndrome: Insights into fetal anomalies beyond conventional imaging techniques.戈尔茨-戈林综合征的尸检7T磁共振成像:对传统成像技术之外的胎儿异常的见解。
Eur J Radiol. 2024 May;174:111390. doi: 10.1016/j.ejrad.2024.111390. Epub 2024 Feb 27.
8
Congenital Tumors-Magnetic Resonance Imaging Findings with Focus on Rare Tumors.先天性肿瘤——磁共振成像表现,重点关注罕见肿瘤
Cancers (Basel). 2023 Dec 20;16(1):43. doi: 10.3390/cancers16010043.
9
Reference Values for Fetal Cardiac Dimensions, Volumes, Ventricular Function and Left Ventricular Longitudinal Strain Using Doppler Ultrasound Gated Cardiac Magnetic Resonance Imaging in Healthy Third Trimester Fetuses.应用超声心动图门控心脏磁共振成像技术测量健康晚期胎儿的心脏结构、容积、心室功能及左室长轴应变的参考值。
J Magn Reson Imaging. 2024 Jul;60(1):365-374. doi: 10.1002/jmri.29077. Epub 2023 Oct 19.
10
Cardiac and Pericardial Neoplasms in Children: Radiologic-Pathologic Correlation.儿童心脏和心包肿瘤:放射-病理相关性。
Radiographics. 2023 Sep;43(9):e230010. doi: 10.1148/rg.230010.