Ekberg M, Holmberg L, Denneberg T
Acta Paediatr Scand. 1977 Nov;66(6):693-8. doi: 10.1111/j.1651-2227.1977.tb07973.x.
The characteristics of the hemolytic-uremic syndrome in 7 children living in a well defined area in the south of Sweden are described. All the patients had a severe form of the disease and were critically ill. The clinical activity could best be followed by measuring blood platelets and urinary FDP. Early institution of hemodialysis treatment, given almost daily until normalisation of platelet count and urinary output, is the most important live-saving measure. Full dosage heparin seems not to be necessary. Six patients survived and were followed-up for 1-7 years. When last seen they all had normal renal function and blood pressure.
本文描述了瑞典南部一个明确区域内7名儿童溶血尿毒综合征的特征。所有患者均患有严重形式的该疾病,病情危急。通过测量血小板和尿FDP能最好地跟踪临床活动情况。早期进行血液透析治疗,几乎每天进行,直至血小板计数和尿量恢复正常,这是最重要的挽救生命的措施。似乎不需要使用全剂量肝素。6名患者存活并接受了1至7年的随访。最后一次检查时,他们的肾功能和血压均正常。