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儿童急性肾衰竭:急性透析治疗后的预后特征

Acute renal failure in children: prognostic features after treatment with acute dialysis.

作者信息

Offner G, Brodehl J, Galaske R, Rutt T

出版信息

Eur J Pediatr. 1986 Feb;144(5):482-6. doi: 10.1007/BF00441743.

Abstract

A 12-year review (1972-1983) is presented of 76 children who were dialysed because of acute renal failure. The causes of acute renal failure were mainly the haemolytic-uraemic syndrome (53%), trauma (16%) and operation (13%). Fifty-eight children (76%) survived, 18 children (24%) died. Fifty-two children, the majority suffering from haemolytic-uraemic syndrome, regained complete or partial renal function after a period of dialysis lasting between 1 and 57 days. One to 7.7 years after dialysis, clearance studies with inulin (CIn), p-aminohippuric acid (CPAH) and phosphate (Tp/CIn) for staging renal function were carried out. The results of this investigation show a significant inverse correlation between the glomerular function regained and the duration of intermittent dialysis.

摘要

本文对1972年至1983年间因急性肾衰竭接受透析治疗的76例儿童进行了为期12年的回顾性研究。急性肾衰竭的主要病因是溶血尿毒综合征(53%)、创伤(16%)和手术(13%)。58例儿童(76%)存活,18例儿童(24%)死亡。52例儿童,其中大多数患有溶血尿毒综合征,在接受1至57天的透析治疗后恢复了完全或部分肾功能。透析后1至7.7年,采用菊粉清除率(CIn)、对氨基马尿酸清除率(CPAH)和磷酸盐清除率(Tp/CIn)进行肾功能分期研究。本研究结果显示,恢复的肾小球功能与间歇性透析持续时间之间存在显著的负相关。

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