细胞松弛素B可阻止重新聚集的胚胎细胞的特定分选。
Cytochalasin B prevents specific sorting of reaggregating embryonic cells.
作者信息
Maslow D E, Mayhew E
出版信息
Science. 1972 Jul 21;177(4045):281-2. doi: 10.1126/science.177.4045.281.
PMID:4114367
Abstract
The effect of cytochalasin B on specific sorting during reaggregation of embryonic chick heart and neural retina cells was studied. At a dose that did not measurably affect uptake of precursors of protein and RNA synthesis, ratios of potassium to sodium ions, and nonspecific aggregation, cytochalasin B disrupted the formation of the characteristic pattern of islands of heart cells within a retinal continuum.
摘要
研究了细胞松弛素B对鸡胚心脏和神经视网膜细胞重聚集过程中特异性分选的影响。在不显著影响蛋白质和RNA合成前体摄取、钾离子与钠离子比例以及非特异性聚集的剂量下，细胞松弛素B破坏了视网膜连续体中心脏细胞岛特征模式的形成。
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