• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Treatment of Parkinson's disease with L-DOPA and decarboxylase inhibitor.

作者信息

Rinne U K, Sonninen V, Sirtola T

出版信息

Z Neurol. 1972;202(1):1-20. doi: 10.1007/BF00316422.

DOI:10.1007/BF00316422
PMID:4114458
Abstract
摘要

相似文献

1
Treatment of Parkinson's disease with L-DOPA and decarboxylase inhibitor.用左旋多巴和脱羧酶抑制剂治疗帕金森病。
Z Neurol. 1972;202(1):1-20. doi: 10.1007/BF00316422.
2
[L-dopa therapy of Parkinson's syndrome. Comparison of pure L-dopa and the combination preparation L-dopa and decarboxylase inhibitor].
Dtsch Med Wochenschr. 1972 Aug 25;97(34):1246-8. doi: 10.1055/s-0028-1107539.
3
[Therapy of Parkinson's syndrome with L-dopa and a decarboxylase inhibitor (Ro 4-4602). Course in 71 patients].[左旋多巴与脱羧酶抑制剂（Ro 4-4602）治疗帕金森综合征。71例患者的病程]
Schweiz Med Wochenschr. 1972 Jan 22;102(3):88-94.
4
L-Dopa treatment in Parkinson's Disease.帕金森病的左旋多巴治疗。
Eur Neurol. 1970;4(6):348-69. doi: 10.1159/000113990.
5
[Treatment of Parkinson's disease with L-dopa combined with a decarboxylase inhibitor].
Dtsch Med Wochenschr. 1969 Dec 26;94(52):2678-81. doi: 10.1055/s-0028-1110503.
6
[Comparison of the effect of L-Dopa and of an L-Dopa+decarboxylase inhibitor combination in Parkinson's disease].
Arch Psychiatr Nervenkr (1970). 1973 Mar 19;217(1):95-112. doi: 10.1007/BF02552835.
7
Acid monoamine metabolites in the cerebrospinal fluid of Parkinsonian patients treated with levodopa alone or combined with a decarboxylase inhibitor.单独使用左旋多巴或与脱羧酶抑制剂联合治疗的帕金森病患者脑脊液中的酸性单胺代谢产物。
Eur Neurol. 1973;9(6):349-62. doi: 10.1159/000114243.
8
Levodopa combined with MK 486 (L-alpha methyldopahydrazine)--a peripheral decarboxylase inhibitor in Parkinson's disease.左旋多巴与MK 486（L-α-甲基多巴肼）联合应用——一种帕金森病外周脱羧酶抑制剂。
Med J Aust. 1974 Mar 23;1(12):429-32.
9
[Experiences in the treatment of Parkinson's disease with a combination drug: L-dopa plus decarboxylase inhibitor (Ro 8-0576)].[联合用药（左旋多巴加脱羧酶抑制剂（Ro 8-0576））治疗帕金森病的经验]
Wien Med Wochenschr. 1973 Jun 30;123(26):433-5.
10
[Treatment of Parkinson's syndrome with L-dopa and a decarboxylase inhibitor].左旋多巴与脱羧酶抑制剂治疗帕金森综合征
Arch Invest Med (Mex). 1974;5(2):105-16.

引用本文的文献

1
Acute administration of L-DOPA induces changes in methylation metabolites, reduced protein phosphatase 2A methylation, and hyperphosphorylation of Tau protein in mouse brain.急性给予左旋多巴会导致甲基化代谢物的变化，降低蛋白磷酸酶 2A 的甲基化，以及小鼠大脑 Tau 蛋白的过度磷酸化。
J Neurosci. 2012 Jul 4;32(27):9173-81. doi: 10.1523/JNEUROSCI.0125-12.2012.
2
Diagnosis and treatment of Parkinson disease: molecules to medicine.帕金森病的诊断与治疗：从分子到医学
J Clin Invest. 2006 Jul;116(7):1744-54. doi: 10.1172/JCI29178.
3
L-dopa level in plasma, primary condition for the kinetic effect.

本文引用的文献

1
SPECIFIC ASSAYS OF SOME PHOSPHATASES IN SUBCELLULAR FRACTIONS OF SMALL INTESTINAL MUCOSA.小肠黏膜亚细胞组分中某些磷酸酶的特异性测定
Nature. 1965 Feb 20;205:799-800. doi: 10.1038/205799a0.
2
On the occurrence of homovanillic acid in brain and cerebrospinal fluid and its determination by a fluorometric method.关于高香草酸在脑和脑脊液中的存在及其荧光法测定
Life Sci (1962). 1963 Jul(7):448-58. doi: 10.1016/0024-3205(63)90132-2.
3
A method for evaluating disability in patients with Parkinson's disease.一种评估帕金森病患者残疾程度的方法。
血浆中左旋多巴水平，这是动力学效应的首要条件。
J Neural Transm. 1973;34(2):133-43. doi: 10.1007/BF01244666.
4
[Comparison of the effect of L-Dopa and of an L-Dopa+decarboxylase inhibitor combination in Parkinson's disease].
Arch Psychiatr Nervenkr (1970). 1973 Mar 19;217(1):95-112. doi: 10.1007/BF02552835.
5
Correlation of clinical symptoms, HVA and 5-HIAA in csf and plasma L-DOPA in Parkinsonian patients treated with L-DOPA and L-DOPA + RO 4-4602.左旋多巴及左旋多巴+RO 4-4602治疗的帕金森病患者临床症状、脑脊液中高香草酸（HVA）和5-羟吲哚乙酸（5-HIAA）与血浆左旋多巴的相关性
Eur J Clin Pharmacol. 1977 Apr 20;11(4):255-61. doi: 10.1007/BF00607673.
6
Levodopa and decarboxylase inhibitors: a review of their clinical pharmacology and use in the treatment of parkinsonism.左旋多巴与脱羧酶抑制剂：其临床药理学及在帕金森病治疗中的应用综述
Drugs. 1976;11(5):329-77. doi: 10.2165/00003495-197611050-00001.
7
L-deprenyl treatment of on-off phenomena in Parkinson's disease.左旋司来吉兰治疗帕金森病的开关现象
J Neural Transm. 1978;43(3-4):253-62. doi: 10.1007/BF01246962.
8
Mortality of patients with Parkinson's disease treated with levodopa.
J Neurol. 1977 Oct 7;216(3):147-53. doi: 10.1007/BF00313615.
9
Levodopa alone and in combination with a peripheral decarboxylase inhibitor benserazide (Madopar) in the treatment of Parkinson's disease: A controlled clinical trial.左旋多巴单独及与外周脱羧酶抑制剂苄丝肼（美多芭）联合用于帕金森病治疗：一项对照临床试验。
J Neurol. 1975 Dec 2;211(1):1-9. doi: 10.1007/BF00312459.
J Nerv Ment Dis. 1961 Aug;133:143-7. doi: 10.1097/00005053-196108000-00010.
4
[The L-3,4-dioxyphenylalanine (DOPA)-effect in Parkinson-akinesia].[左旋多巴（L-3,4-二羟基苯丙氨酸）对帕金森氏症运动不能的作用]
Wien Klin Wochenschr. 1961 Nov 10;73:787-8.
5
Drug-induced changes in the concentration of 5-OR indolyl compounds in cerebrospinal fluid and caudate nucleus.药物引起的脑脊液和尾状核中5-羟色胺吲哚化合物浓度的变化。
Br J Pharmacol Chemother. 1962 Aug;19(1):153-60. doi: 10.1111/j.1476-5381.1962.tb01436.x.
6
[Distribution of noradrenaline and dopamine (3-hydroxytyramine) in the human brain and their behavior in diseases of the extrapyramidal system].[去甲肾上腺素和多巴胺（3-羟酪胺）在人脑内的分布及其在锥体外系疾病中的表现]
Klin Wochenschr. 1960 Dec 15;38:1236-9. doi: 10.1007/BF01485901.
7
Increase of cerebral catecholamines caused by 3,4-dihydroxyphenylalanine after inhibition of peripheral decarboxylase.外周脱羧酶抑制后，3,4-二羟基苯丙氨酸引起脑内儿茶酚胺增加。
Nature. 1967 Aug 19;215(5103):852-3. doi: 10.1038/215852b0.
8
Treatment of parkinsonism with levodopa.左旋多巴治疗帕金森症。
Arch Neurol. 1969 Oct;21(4):343-54. doi: 10.1001/archneur.1969.00480160015001.
9
Behavioral and biochemical effects of L-dopa after peripheral decarboxylase inhibition.外周脱羧酶抑制后左旋多巴的行为和生化效应。
Brain Res. 1969 Sep;15(1):233-42. doi: 10.1016/0006-8993(69)90322-9.
10
Further studies on tryptophan hydroxylase in rat brainstem and beef pineal.大鼠脑干和牛松果体中色氨酸羟化酶的进一步研究。
Biochem Pharmacol. 1969 May;18(5):1071-81. doi: 10.1016/0006-2952(69)90111-7.