Irwin M R
Proc Natl Acad Sci U S A. 1972 Oct;69(10):2979-81. doi: 10.1073/pnas.69.10.2979.
Two of the antigenic characters of erythrocytes, that in either identical or related forms differentiate four species of Streptopelia (chinensis, humilis, orientalis, and senegalensis) from a fifth (S. risoria) by interaction of the causative genes, are involved in the appearance in backcross hybrids of additional antigenic specificities to those of the parental species. The cells of backcross hybrids, resulting from matings of S. chinensis x S. risoria and backcrossing to S. risoria, in which the two independently inherited antigenic characters (ch-4 and ch-8 peculiar to S. chinensis) are combined as homozygotes, exhibit an antigenic specificity not present in backcross birds carrying separately these two characters. This result indicates an interaction within S. chinensis of the genes for these two antigenic characters. An antigen (C(g)) by which Columba guinea differs from C. livia has behaved as a unit in over 400 backcross offspring. It is antigenically related to both ch-4 and ch-8 of S. chinensis. It is also related to, but not identical with, this interaction antigen of S. chinensis. Further, the C(g) character is also related to an interaction product that appears in all backcross offspring carrying the group-4 antigen in a S. risoria genome. Genes related to those that in modern species or in species hybrids interact to effect new antigenic specificities presumably possessed the same abilities in ancestral forms of Columbidae.
红细胞的两种抗原特性，以相同或相关形式通过致病基因的相互作用，将四种珠颈斑鸠（中华珠颈斑鸠、淡腹珠颈斑鸠、灰斑鸠和塞内加尔斑鸠）与第五种（家鸽）区分开来，这两种抗原特性在回交杂种中会产生除亲本物种之外的其他抗原特异性。中华珠颈斑鸠与家鸽杂交并回交到家鸽产生的回交杂种细胞中，两个独立遗传的抗原特性（中华珠颈斑鸠特有的ch - 4和ch - 8）作为纯合子结合在一起，表现出单独携带这两个特性的回交鸟类所没有的抗原特异性。这一结果表明中华珠颈斑鸠中这两个抗原特性的基因之间存在相互作用。几内亚鸽与原鸽不同的一种抗原（C(g)）在400多个回交后代中表现为一个单位。它在抗原性上与中华珠颈斑鸠的ch - 4和ch - 8都相关。它也与中华珠颈斑鸠的这种相互作用抗原相关，但并不相同。此外，C(g)特性还与一种相互作用产物相关联，这种产物出现在所有在家鸽基因组中携带4组抗原的回交后代中。与现代物种或物种杂种中相互作用以产生新抗原特异性的基因相关的基因，在鸽科的祖先形式中可能也具有相同的能力。
