高柠檬酸合酶作为赖氨酸影响青霉素生物合成的关键位点。
Homocitrate synthase as the crucial site of the lysine effect on penicillin biosynthesis.
作者信息
Friedrich C G, Demain A L
出版信息
J Antibiot (Tokyo). 1977 Sep;30(9):760-1. doi: 10.7164/antibiotics.30.760.
PMID:411778
Abstract
Homocitrate reverses the lysine inhibition of penicillin bisynthesis. Since lysine is known to inhibit homocitrate synthase, reversal by the reaction product identifies this enzyme as the crucial site of the lysine effect.
摘要
高柠檬酸可逆转赖氨酸对青霉素生物合成的抑制作用。由于已知赖氨酸会抑制高柠檬酸合酶，因此反应产物的逆转作用表明该酶是赖氨酸发挥作用的关键位点。
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