Hanai K, Adachi H, Ogasawara H
J Bone Joint Surg Br. 1977 Nov;59-B(4):481-4. doi: 10.1302/0301-620X.59B4.411796.
Ossification of the posterior longitudinal ligament in the cervical region is generally regarded as a rare disease, though a Japanese series of 185 cases has been reported. The main symptoms arise from a myelopathy, the degree of which varies from moderate to severe, due to stenosis of the spinal canal. In order to clarify the relationship between the severity of symptoms and the cross-sectional area of ossification, axial transverse tomography of the cervical spine has been carried out on twenty-six patients at intervals of 5 millimetres over the full extent of the ossification. In this way the cross-sectional areas of the ossified tissue and of the spinal canal were calculated. The former varied from a minimum of 0.8 to a maximum of 1.8 square centimetres. In cases of severe myelopathy the ossification was mainly at the fourth and fifth cervical levels and the stenosis ration exceeded 30 per cent.
尽管已有报道称日本有一系列185例病例,但颈椎后纵韧带骨化通常被视为一种罕见疾病。主要症状源于脊髓病,由于椎管狭窄,其程度从中度到重度不等。为了阐明症状严重程度与骨化横截面积之间的关系,对26例患者的颈椎进行了轴向断层扫描,在骨化的整个范围内每隔5毫米进行一次扫描。通过这种方式计算了骨化组织和椎管的横截面积。前者的变化范围从最小0.8平方厘米到最大1.8平方厘米。在严重脊髓病的病例中,骨化主要发生在颈椎第四和第五节段,狭窄率超过30%。