Nayak D P
J Virol. 1972 Nov;10(5):933-6. doi: 10.1128/JVI.10.5.933-936.1972.
Herpesvirus (GPHV) antigen is either present in very small amounts, or absent in leukemic lymphoblasts taken directly from strain 2 guinea pigs. However, after maintenance in tissue culture for 72 hr, almost 100% of these lymphoblasts contained GPHV antigen. The expression of GPHV antigen could be demonstrated by indirect immunofluorescent technique as well as by the direct (125)I labeled antibody technique. However, infectious virus or virus capsids could not be detected in these cells either by infectivity tests or electron microscopy.
疱疹病毒(GPHV)抗原在直接取自2号品系豚鼠的白血病淋巴母细胞中要么含量极少,要么不存在。然而,在组织培养中维持72小时后,几乎100%的这些淋巴母细胞都含有GPHV抗原。GPHV抗原的表达可以通过间接免疫荧光技术以及直接(125)I标记抗体技术来证明。然而,通过感染性试验或电子显微镜在这些细胞中均未检测到传染性病毒或病毒衣壳。