Lahti R A
Naturwissenschaften. 1979 Aug;66(8):403-9. doi: 10.1007/BF00368070.
Numerous studies have been reviewed concerning the relationship of the catecholamines and indoleamines to depression and its treatment with antidepressant drugs. The profusion of data on the subject suggests the amines may be implicated in the disease, however no convincing hypothesis is available which unites the two. A similar situation seems to exist concerning the antipsychotic agents, dopamine and schizophrenia. The evidence appears to be overwhelming relating dopamine in the action of these agents and yet serious inconsistencies have been reported suggesting the need for a revision of the hypothesis regarding the mode of action of antipsychotic agents.
关于儿茶酚胺和吲哚胺与抑郁症及其抗抑郁药物治疗之间的关系，已有大量研究被综述。关于该主题的大量数据表明，胺类物质可能与该疾病有关，然而目前尚无令人信服的假说来将两者联系起来。在抗精神病药物、多巴胺和精神分裂症方面似乎也存在类似情况。有压倒性的证据表明多巴胺与这些药物的作用有关，但也有报道称存在严重的不一致性，这表明需要对关于抗精神病药物作用模式的假说进行修正。
