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The tricyclic antidepressants--inhibition of norepinephrine uptake as related to potentiation of norepinephrine and clinical efficacy.

作者信息

Lahti R A, Maickel R P

出版信息

Biochem Pharmacol. 1971 Feb;20(2):482-6. doi: 10.1016/0006-2952(71)90086-4.

DOI:10.1016/0006-2952(71)90086-4
PMID:5150145
Abstract
摘要

相似文献

1
The tricyclic antidepressants--inhibition of norepinephrine uptake as related to potentiation of norepinephrine and clinical efficacy.三环类抗抑郁药——去甲肾上腺素摄取抑制与去甲肾上腺素增强及临床疗效的关系。
Biochem Pharmacol. 1971 Feb;20(2):482-6. doi: 10.1016/0006-2952(71)90086-4.
2
Blocking H 3 -Norepinephrine uptake and some guanethidine-induced effects with tricyclic psychotherapeutic drugs.用三环类精神治疗药物阻断H3-去甲肾上腺素摄取及胍乙啶诱导的某些效应。
Arch Int Pharmacodyn Ther. 1972 Jan;195(1):71-80.
3
[Central determination of the hyperthermic effect and its potentiation by antidepressants during administration of large doses of norepinephrine into the mouse cerebral ventricle].[在向小鼠脑室注射大剂量去甲肾上腺素期间，中枢对热效应的测定及其被抗抑郁药增强的作用]
Biull Eksp Biol Med. 1973 Nov;76(11):80-3.
4
Effects of butriptyline and structurally-related drugs on norepinephrine uptake and gastric acid secretion in rodents.布替林及结构相关药物对啮齿动物去甲肾上腺素摄取及胃酸分泌的影响。
J Med. 1971;2(5):250-7.
5
Concerning the molecular requirements for the inhibition of the uptake of racemic 3 H-norepinephrine into rat cerebral cortex slices by tricyclic antidepressants and related compounds.关于三环类抗抑郁药及相关化合物抑制外消旋3H-去甲肾上腺素摄取进入大鼠大脑皮层切片的分子要求。
J Pharmacol Exp Ther. 1971 Sep;178(3):474-81.
6
Kinetic and thermodynamic considerations regarding the inhibition by tricyclic antidepressants of the uptake of tritiated norepinephrine by the adrenergic nerves in rabbit aortic strips.关于三环类抗抑郁药对兔主动脉条中肾上腺素能神经摄取氚化去甲肾上腺素的抑制作用的动力学和热力学考量。
J Pharmacol Exp Ther. 1970 Jan;171(1):62-9.
7
Blockade of noradrenaline uptake and inhibition of gastric acid secretion by 2-[p-chlorophenyl-2-(pyridyl)hydroxymethyl] imidazoline maleate (Sch-12650).马来酸2-[对氯苯基-2-(吡啶基)羟甲基]咪唑啉（Sch-12650）对去甲肾上腺素摄取的阻断及胃酸分泌的抑制作用
J Pharm Pharmacol. 1970 May;22(5):387-8. doi: 10.1111/j.2042-7158.1970.tb08548.x.
8
Effect of desmethylimipramine, iprindole and DL-erythro-alpha-(3,4-dichlorophenyl)-beta-(t-butyl amino) propanol HC1 on the metabolism of amphetamine.去甲丙咪嗪、茚满二酮和盐酸 DL-赤藓醇-α-(3,4-二氯苯基)-β-(叔丁基氨基)丙醇对苯丙胺代谢的影响。
Biochem Pharmacol. 1970 Dec;19(12):3021-8. doi: 10.1016/0006-2952(70)90088-2.
9
The effect of various phenothiazines and tricyclic antidepressants on the accumulation and release of (3H)norepinephrine and (3H)5-hydroxytryptamine in slices of rat occipital cortex.
Res Commun Chem Pathol Pharmacol. 1976 Feb;13(2):237-50.
10
Effects of methotrimeprazine, other phenothiazines and related compounds on the levels of norepinephrine in the mouse heart.
J Pharmacol Exp Ther. 1967 Aug;157(2):363-70.

引用本文的文献

1
Behavioural changes during withdrawal from desmethylimipramine (DMI). II. Increased resistance to extinction.去甲丙咪嗪（DMI）戒断期间的行为变化。II. 消退抗性增加。
Psychopharmacology (Berl). 1981;75(1):60-4. doi: 10.1007/BF00433503.
2
Structure-activity relations for the inhibition of 5-hydroxytryptamine uptake by tricyclic antidepressants into synaptosomes from serotoninergic neurones in rat brain homogenates.三环类抗抑郁药对大鼠脑匀浆中5-羟色胺能神经元突触体摄取5-羟色胺的抑制作用的构效关系。
Br J Pharmacol. 1974 Jul;51(3):399-403. doi: 10.1111/j.1476-5381.1974.tb10675.x.
3
Effect of iprindole on norepinephrine turnover and transport.
丙咪吲哚对去甲肾上腺素周转及转运的影响。
Psychopharmacologia. 1974;40(1):53-64. doi: 10.1007/BF00429447.
4
Effect of iprindole on the metabolism of trimipramine in the rat.吲哚洛尔对大鼠体内三甲丙咪嗪代谢的影响。
J Psychiatry Neurosci. 1991 Dec;16(5):272-5.
5
Effects of iprindole on responses of single cortical and caudate neurones to monoamines and acetylcholine.吲哚洛尔对单个皮层和尾状核神经元对单胺类和乙酰胆碱反应的影响。
Br J Pharmacol. 1975 Sep;55(1):17-25. doi: 10.1111/j.1476-5381.1975.tb07605.x.
6
Arrhythmias and inhibition of noradrenaline uptake caused by tricyclic antidepressants and chlorpromazine on the isolated perfused rabbit heart.三环类抗抑郁药和氯丙嗪对离体灌注兔心脏的心律失常及去甲肾上腺素摄取抑制作用
Naunyn Schmiedebergs Arch Pharmacol. 1975;288(2-3):215-31. doi: 10.1007/BF00500528.
7
The effect of amitriptyline, desipramine and imipramine on the vivo brain synthesis of 3H-noradrenaline from 3H-L-dopa in the rat.阿米替林、去甲丙咪嗪和丙咪嗪对大鼠体内由3H-L-多巴合成3H-去甲肾上腺素的影响。
Psychopharmacologia. 1975;41(3):249-54. doi: 10.1007/BF00428932.
8
Effects of antidepressant drugs on noradrenaline accumulation and contractile responses in the rat anococcygeus muscle.抗抑郁药物对大鼠肛尾肌去甲肾上腺素蓄积及收缩反应的影响。
Br J Pharmacol. 1977 Mar;59(3):403-9. doi: 10.1111/j.1476-5381.1977.tb08393.x.
9
Decrease in brain NE turnover after chronic DMI treatment; no effect with iprindole.慢性地昔帕明治疗后大脑去甲肾上腺素周转率降低；茚满丙二胺无此作用。
Psychopharmacology (Berl). 1978 Apr 11;56(3):335-41. doi: 10.1007/BF00432858.
10
A possible common mechanism of action of antidepressant treatments: reduction in the sensitivity of the noradrenergic cyclic AMP gererating system in the rat limbic forebrain.抗抑郁治疗的一种可能的共同作用机制：降低大鼠边缘前脑去甲肾上腺素能环磷酸腺苷生成系统的敏感性。
Naunyn Schmiedebergs Arch Pharmacol. 1976 May;293(2):109-14. doi: 10.1007/BF00499215.