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人工智能在肾脏疾病与透析中的应用:从数据挖掘到临床影响

Artificial intelligence in kidney disease and dialysis: from data mining to clinical impact.

作者信息

Neri Luca, Zhang Hanjie, Usvyat Len A

机构信息

Renal Research Institute, New York, New York, USA.

出版信息

Curr Opin Nephrol Hypertens. 2026 Jan 1;35(1):30-35. doi: 10.1097/MNH.0000000000001132. Epub 2025 Nov 7.

Abstract

PURPOSE OF REVIEW

Artificial intelligence (AI) and machine learning (ML) are rapidly transforming healthcare, but their adoption in nephrology and dialysis remains relatively limited.

RECENT FINDINGS

This review highlights key applications of AI in kidney disease, including prognostic modeling, imaging, personalized anemia and fluid management, patient engagement, and research acceleration. While numerous studies demonstrate improved prediction accuracy and clinical insights, translation into routine practice is rare. Examples such as the Anemia Control Model (ACM) demonstrate that AI can simultaneously improve clinical outcomes and reduce costs, though widespread adoption will require rigorous validation, seamless integration into clinical workflows, regulatory approval, and above all, clinician trust.

SUMMARY

AI in nephrology shows promise for personalized care and cost reduction, as demonstrated by tools like the Anemia Control Model. Yet, broad adoption requires rigorous validation, seamless workflow integration, regulatory clearance, and clinician trust. Future opportunities include digital twins, large language models, and multiomics integration, with AI poised to enhance both patient outcomes and system performance.

摘要

综述目的

人工智能(AI)和机器学习(ML)正在迅速改变医疗保健领域,但它们在肾脏病学和透析中的应用仍然相对有限。

最新发现

本综述重点介绍了AI在肾脏疾病中的关键应用,包括预后建模、成像、个性化贫血和液体管理、患者参与以及加速研究。虽然众多研究表明预测准确性和临床见解有所改善,但转化为常规实践的情况却很少见。贫血控制模型(ACM)等例子表明,AI可以同时改善临床结果并降低成本,不过广泛采用需要严格验证、无缝集成到临床工作流程、监管批准,最重要的是,获得临床医生的信任。

总结

正如贫血控制模型等工具所证明的那样,肾脏病学中的AI有望实现个性化护理并降低成本。然而,广泛采用需要严格验证、无缝工作流程集成、监管许可和临床医生的信任。未来的机会包括数字孪生、大语言模型和多组学整合,AI有望改善患者结局和系统性能。

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