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荧光素二月桂酸酯口服胰腺功能试验的临床价值(作者译)

[The clinical value of an oral test of pancreatic function with fluorescein dilaurate (author's transl)].

作者信息

Kaffernik H, Klimkeit P, Zöfel P, Otte U, Meyer-Bertenrath J G

出版信息

MMW Munch Med Wochenschr. 1977 Nov 11;119(45):1467-70.

PMID:412095
Abstract

Exocrine insufficiency of the pancreas was identified by decreased splitting of the ester substrate and thus diminished excretion of fluorescein in the urine of persons with normal pancreatic function (test excretion). Unesterified fluorescein served to ascertain the standard excretion of fluorescein (= 100%). The relation of test excretion to standard excretion was expressed in %. Values of less than 20% in collected urine are pathologic. The range of 20-30% is questionable. Normal persons showed 30% or more. The method described is simple and without problems for the patient. The test was accurate in 93% of patients with a false negative in 1%. Practicability and results recommend the test as a screening method.

摘要

胰腺外分泌功能不全通过酯底物分解减少来确定,因此胰腺功能正常者尿液中荧光素排泄减少(试验排泄)。未酯化的荧光素用于确定荧光素的标准排泄量(=100%)。试验排泄与标准排泄的关系以百分比表示。收集尿液中值低于20%为病理性。20 - 30%的范围存疑。正常人显示为30%或更高。所描述的方法简单,对患者无问题。该试验在93%的患者中准确,假阴性率为1%。实用性和结果推荐该试验作为一种筛查方法。

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