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用感染拟分枝孢镰刀菌的大麦籽粒提取物处理的小鼠的肝癌发生及血清甲胎蛋白的出现

Hepatocarcinogenesis and the appearance of serum alpha-fetoprotein in mice treated with extracts of barley grain infected with Fusarium sporotrichioides.

作者信息

Akhmeteli M A, Linnik A B, Cernov K S

出版信息

Bull World Health Organ. 1972;47(5):663-4.

PMID:4121669
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2480846/
Abstract

Experiments demonstrated a significant association between the presence of tumours in mice and AFP positivity, while AFP negativity was usually associated with the absence of tumours. The presence of AFP in the serum of tumour-bearing mice was possibly related to treatment with F. sporotrichioides extract.

摘要

实验表明，小鼠体内肿瘤的存在与甲胎蛋白阳性之间存在显著关联，而甲胎蛋白阴性通常与无肿瘤相关。荷瘤小鼠血清中甲胎蛋白的存在可能与用申克孢子丝菌提取物治疗有关。

相似文献

1
Hepatocarcinogenesis and the appearance of serum alpha-fetoprotein in mice treated with extracts of barley grain infected with Fusarium sporotrichioides.用感染拟分枝孢镰刀菌的大麦籽粒提取物处理的小鼠的肝癌发生及血清甲胎蛋白的出现
Bull World Health Organ. 1972;47(5):663-4.
2
Study of extracts of barley grain infected with Fusarium sporotrichioides No. 63.对感染了63号串珠镰刀菌的大麦籽粒提取物的研究。
Bull World Health Organ. 1972;47(1):123-4.
3
[Alpha-l-fetoprotein. Introductory biological description].[甲胎蛋白。生物学初步描述]
Ann Gastroenterol Hepatol (Paris). 1971 Nov-Dec;7(6):533-9.
4
[Diagnosis of hepatoma using alpha 1-foetospecific serum protein (alpha-fetoprotein)].[利用α1-胎儿特异性血清蛋白（甲胎蛋白）诊断肝癌]
Gan No Rinsho. 1971;17(9):687-91.
5
[The alpha-1-fetoprotein test in the diagnosis of hepatocellular carcinoma].[甲胎蛋白检测在肝细胞癌诊断中的应用]
Rev Clin Esp. 1972 Jan 31;124(2):109-14.
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[Production of alpha-1-fetoprotein during the course of primary carcinoma of the liver (apropos of 83 cases)].[原发性肝癌病程中α-1-甲胎蛋白的产生（附83例报告）]
Arch Fr Mal App Dig. 1971 Dec;60(12):615-28.
7
[Alpha-1-feto-protein and primary cancer of the liver].[甲胎蛋白与原发性肝癌]
Ann Gastroenterol Hepatol (Paris). 1971 Nov-Dec;7(6):551-60.
8
Effect of antigen excess on detection of alpha-fetoprotein by counterelectrophoresis.
Ann Clin Lab Sci (1971). 1972 Nov-Dec;2(6):456-8.
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[Serum alpha-1-fetoprotein (AFP) in the immunological diagnosis of primary hepatoma].[血清甲胎蛋白（AFP）在原发性肝癌免疫诊断中的应用]
Med Interna (Bucur). 1973 Aug;25(8):955-62.
10
[Serological examinations in children with hepatoma and teratoma of alpha-fetoprotein and alpha-2-H-globulin and the diagnostic and prognostic value (author's transl)].[肝癌和畸胎瘤患儿甲胎蛋白及α-2-H球蛋白的血清学检查及其诊断和预后价值（作者译）]
Padiatr Padol. 1973;8(1):40-4.

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Circulating predictive and diagnostic biomarkers for hepatitis B virus-associated hepatocellular carcinoma.乙型肝炎病毒相关肝细胞癌的循环预测性和诊断性生物标志物
World J Gastroenterol. 2016 Oct 7;22(37):8271-8282. doi: 10.3748/wjg.v22.i37.8271.
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Mycotoxin induction of somatic mosaicism in Drosophila and DNA repair in mammalian liver cell cultures.
Cell Biol Toxicol. 1985 Jun;1(3):133-43. doi: 10.1007/BF00120160.
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Lack of mutagenicity to Salmonella typhimurium of some Fusarium mycotoxins.某些镰刀菌霉菌毒素对鼠伤寒沙门氏菌无致突变性。
Appl Environ Microbiol. 1978 Apr;35(4):659-62. doi: 10.1128/aem.35.4.659-662.1978.
4
[Carcinofetal antigens. I. alpha-fetoprotein (author's transl)].[癌胚抗原。I. 甲胎蛋白（作者译）]
Klin Wochenschr. 1975 Feb 15;53(4):147-69. doi: 10.1007/BF01466760.

本文引用的文献

1
Study of extracts of barley grain infected with Fusarium sporotrichioides No. 63.对感染了63号串珠镰刀菌的大麦籽粒提取物的研究。
Bull World Health Organ. 1972;47(1):123-4.
2
Association of embryonic antigens with experimentally induced hepatic lesions in the rat.胚胎抗原与大鼠实验性诱导肝损伤的关联。
Cancer Res. 1967 Nov;27(11):1990-7.
3
[Interference of aflatoxin in protein synthesis in rats. Immunologic study].
C R Seances Soc Biol Fil. 1969;163(1):274-7.