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用感染拟分枝孢镰刀菌的大麦籽粒提取物处理的小鼠的肝癌发生及血清甲胎蛋白的出现

Hepatocarcinogenesis and the appearance of serum alpha-fetoprotein in mice treated with extracts of barley grain infected with Fusarium sporotrichioides.

作者信息

Akhmeteli M A, Linnik A B, Cernov K S

出版信息

Bull World Health Organ. 1972;47(5):663-4.

Abstract

Experiments demonstrated a significant association between the presence of tumours in mice and AFP positivity, while AFP negativity was usually associated with the absence of tumours. The presence of AFP in the serum of tumour-bearing mice was possibly related to treatment with F. sporotrichioides extract.

摘要

实验表明,小鼠体内肿瘤的存在与甲胎蛋白阳性之间存在显著关联,而甲胎蛋白阴性通常与无肿瘤相关。荷瘤小鼠血清中甲胎蛋白的存在可能与用申克孢子丝菌提取物治疗有关。

引用本文的文献

1
Circulating predictive and diagnostic biomarkers for hepatitis B virus-associated hepatocellular carcinoma.
World J Gastroenterol. 2016 Oct 7;22(37):8271-8282. doi: 10.3748/wjg.v22.i37.8271.
3
Lack of mutagenicity to Salmonella typhimurium of some Fusarium mycotoxins.
Appl Environ Microbiol. 1978 Apr;35(4):659-62. doi: 10.1128/aem.35.4.659-662.1978.
4
[Carcinofetal antigens. I. alpha-fetoprotein (author's transl)].
Klin Wochenschr. 1975 Feb 15;53(4):147-69. doi: 10.1007/BF01466760.

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