Ying Xiaoxiao, Huang Luqiao, Yu Feng, Xu Chan
Ostomy Nursing Clinics, Tongde Hospital of Zhejiang Province Affiliated to Zhejiang Chinese Medical University, Hangzhou, China.
Department of Anorectal Surgery, Southeast University Affiliated Xuzhou Central Hospital, Xuzhou, China.
Int Wound J. 2025 Nov;22(11):e70794. doi: 10.1111/iwj.70794.
Irritant contact dermatitis is a common peristomal skin complication. Due to the continuous irritation from intestinal fluids and faeces, the healing of this dermatitis is slow and the condition severely impairs patients' quality of life. The study aimed to evaluate the efficacy of a modified insertable ostomy appliance in promoting healing and improving patient outcomes. A randomised controlled trial was conducted from January 2022 to December 2024 in a tertiary hospital. The enrolled patients, all diagnosed with irritant contact dermatitis, were randomly assigned to two groups. The control group wore the conventional two-piece ostomy appliance, while the experimental group wore the modified insertable ostomy appliance. Outcomes were assessed on Days 3, 7, 14 and 28. The primary outcome was the healing rate (Discoloration, Erosion and Tissue overgrowth [DET] score ≤ 2) at Day 28. Secondary outcomes included the DET score, Visual Analogue Scale (VAS) pain score, Stoma Quality of Life questionnaire (Stoma-QOL) score and the incidence of appliance leakage. A total of 89 eligible participants completed the trial. The experimental group showed a significantly higher 28-day healing rate (73.3% vs. 29.5%, p < 0.001), lower DET scores (Day 28: 2.0 vs. 4.5, p < 0.001), reduced VAS scores (Day 28: 1.5 vs. 2.0, p < 0.001), higher Stoma-QOL scores (Day 28: 55.67 vs. 51.64, p < 0.001) and lower leakage rate (13.3% vs. 93.2%, p < 0.001). The modified ostomy appliance significantly improves healing, reduces pain and enhances quality of life, representing a novel solution for clinical practice.
刺激性接触性皮炎是一种常见的造口周围皮肤并发症。由于肠液和粪便的持续刺激，这种皮炎的愈合缓慢，病情严重影响患者的生活质量。该研究旨在评估一种改良的可插入式造口器具在促进愈合和改善患者预后方面的疗效。2022年1月至2024年12月在一家三级医院进行了一项随机对照试验。所有入选患者均被诊断为刺激性接触性皮炎，随机分为两组。对照组佩戴传统的两件式造口器具，而实验组佩戴改良的可插入式造口器具。在第3、7、14和28天评估结果。主要结局是第28天的愈合率（色素沉着、糜烂和组织过度生长[DET]评分≤2）。次要结局包括DET评分、视觉模拟量表（VAS）疼痛评分、造口生活质量问卷（Stoma-QOL）评分和器具渗漏发生率。共有89名符合条件的参与者完成了试验。实验组的28天愈合率显著更高（73.3%对29.5%，p<0.001），DET评分更低（第28天：2.0对4.5，p<0.001），VAS评分降低（第28天：1.5对2.0，p<0.001），Stoma-QOL评分更高（第28天：55.67对51.64，p<0.001），渗漏率更低（13.3%对93.2%，p<0.001）。改良的造口器具显著改善了愈合情况，减轻了疼痛，提高了生活质量，是临床实践的一种新解决方案。
