Brady Richard R W, Sheard Diane, Howard Kevin, Vestergaard Martin, Boisen Esben Bo, Mather Rebecca, Ainsworth Rachel, Hansen Helle Doré, Ajslev Teresa Adeltoft
Newcastle Centre for Bowel Disease Research Hub, Newcastle Hospitals and Newcastle University, Newcastle upon Tyne NE1 4LP, UK.
Lancashire Teaching Hospital, Royal Preston Hospital, Preston PR2 9HT, UK.
Nurs Rep. 2025 Mar 19;15(3):107. doi: 10.3390/nursrep15030107.
It is well established that having a stoma can negatively impact health-related quality of life (HRQoL), but there is a paucity of research describing the natural history of certain complications associated with living with a stoma, such as leakage and peristomal skin complications (PSCs), and whether these affect QoL within the first year of stoma surgery. The objective of this study was to investigate the pattern of such complications and impact on QoL in individuals who had stoma surgery within the preceding year. A cross-sectional study was conducted at three hospital sites in the United Kingdom to evaluate the burden of disease in those who had undergone intestinal stoma formation surgery within the preceding year. The study consisted of a one-to-one consultation with a study nurse and the completion of an online questionnaire by the patient (ISRCTN-registry: 23080097). The nurse-led interview directly evaluated peristomal skin health, whilst the online questionnaire evaluated the impact of leakage (using the Ostomy Leak Impact tool), generic mental well-being (by WHO-5) and wider HRQoL (by EQ-5D-5L). A total of 114 individuals with an intestinal stoma completed the evaluations. The participants had a mean age of 55.8 years (range 18-87 years) and 58% were male. Forty-three percent of the participants had experienced leakage of stomal effluent outside the baseplate (e.g., onto clothes) in the preceding two weeks and 85% suffered from PSCs ranging from mild (35%), to moderate (18%), and severe (32%). Leakage and PSCs were associated with lower mental well-being and HRQoL ( < 0.05). Leakage events, HRQoL, mental well-being and peristomal skin health were similar for individuals across different timepoints from the time of surgery within the first year. This study reported a high disease burden in people with a new intestinal stoma. Experiencing frequent leakage incidents and/or living with severe PSCs were associated with reduced HRQoL and mental well-being.
造口会对健康相关生活质量（HRQoL）产生负面影响，这一点已得到充分证实，但关于造口相关特定并发症（如渗漏和造口周围皮肤并发症（PSC））的自然病史，以及这些并发症在造口手术后第一年内是否会影响生活质量的研究却很少。本研究的目的是调查前一年接受造口手术的个体中此类并发症的模式及其对生活质量的影响。在英国的三个医院地点进行了一项横断面研究，以评估前一年接受肠道造口形成手术的患者的疾病负担。该研究包括与研究护士进行一对一咨询以及患者完成在线问卷（ISRCTN注册编号：23080097）。由护士主导的访谈直接评估造口周围皮肤健康状况，而在线问卷评估渗漏的影响（使用造口渗漏影响工具）、一般心理健康状况（通过WHO-5）和更广泛的健康相关生活质量（通过EQ-5D-5L）。共有114名肠道造口患者完成了评估。参与者的平均年龄为55.8岁（范围18 - 87岁），58%为男性。43%的参与者在过去两周内经历过造口流出物在底盘外渗漏（例如，渗漏到衣服上），85%的人患有PSC，程度从轻度（35%）到中度（18%）再到重度（32%）。渗漏和PSC与较低的心理健康状况和健康相关生活质量相关（<0.05）。在术后第一年内，不同时间点的个体在渗漏事件、健康相关生活质量、心理健康状况和造口周围皮肤健康方面相似。本研究报告了新的肠道造口患者的高疾病负担。频繁发生渗漏事件和/或患有严重的PSC与健康相关生活质量和心理健康状况下降有关。
