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重症肌无力及其他神经肌肉疾病中的阶梯现象(作者译)

[The staircase phenomenon in myasthenia gravis and other neuromuscular disorders (author's transl)].

作者信息

Meienberg O, Ludin H P

出版信息

EEG EMG Z Elektroenzephalogr Elektromyogr Verwandte Geb. 1977 Dec;8(4):192-4.

PMID:412656
Abstract

The isometric contractions with repetitive stimulation of 2/sec during 90 sec have been recorded in 39 patients with neuromuscular disorders other than myasthenia gravis. Seven patients had falling amplitudes of the contractions, in 14 cases the increase was below 12 per cent and 21 patients had a normal staircase phenomenon. It is recommended to take only a falling of the contraction amplitudes as an important indication for myasthenia gravis. This finding, however, is not specific and in the indivisual case it has to be considered in combination with the other clinical, electro-physiological and histological findings.

摘要

在39例非重症肌无力的神经肌肉疾病患者中记录了在90秒内以2次/秒的频率重复刺激时的等长收缩情况。7例患者收缩幅度下降,14例患者收缩幅度增加低于12%,21例患者有正常的阶梯现象。建议仅将收缩幅度下降作为重症肌无力的重要指征。然而,这一发现并不具有特异性,在个别病例中,必须结合其他临床、电生理和组织学检查结果进行综合考虑。

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