Martin L N, Leslie G A
Immunology. 1977 Dec;33(6):865-72.
A proportion of lymphocytes in blood, spleen and lymph nodes of nonhuman primates had immunoglobulin on their surfaces detectable by fluorescent antibody to human IgM and IgD. The majority of the individual lymphocytes having either IgM or IgD on their surfaces possessed both classes of immunoglobulin. Lymphocyte surface IgD was capped independently of surface IgM on the same cell when incubated at 37 degrees with anti-IgD. Lymphocytes with surface IgM and/or IgD were present in blood at birth and the percentages over the first 6 months of life were increased compared to older monkeys. A corona of cells faintly positive for both IgM and IgD was observed around germinal centres of both lymph nodes and spleen.
非人类灵长类动物血液、脾脏和淋巴结中的一部分淋巴细胞表面有免疫球蛋白，可通过抗人IgM和IgD荧光抗体检测到。大多数表面带有IgM或IgD的单个淋巴细胞同时拥有这两类免疫球蛋白。当在37℃与抗IgD一起孵育时，淋巴细胞表面的IgD可独立于同一细胞表面的IgM形成帽状。出生时血液中就存在表面带有IgM和/或IgD的淋巴细胞，与年龄较大的猴子相比，出生后头6个月这些细胞的百分比有所增加。在淋巴结和脾脏的生发中心周围观察到一圈对IgM和IgD均呈弱阳性的细胞。
