胸腺抑制细胞。I. 具有抑制活性的亚群的分离。
The thymic suppressor cell. I. Separation of subpopulations with suppressor activity.
作者信息
Ha T Y, Waksman B H, Treffers H P
出版信息
J Exp Med. 1974 Jan 1;139(1):13-23. doi: 10.1084/jem.139.1.13.
Abstract
This study confirms the finding that washed thymocytes from rats given 100 mg of BGG 48 h earlier, when transferred to syngeneic recipients, exert a specific suppressor effect on immunological responses to BGG in the latter. The active cells are found in a subpopulation of low density, making up less than 10% of the total thymocytes, and are partially resistant to hydrocortisone.
摘要
本研究证实了以下发现
给大鼠提前48小时注射100毫克BGG后，所获得的经洗涤的胸腺细胞，当转移至同基因受体时，会对后者针对BGG的免疫反应产生特异性抑制作用。活性细胞存在于低密度亚群中，占胸腺细胞总数的比例不到10%，并且对氢化可的松具有部分抗性。
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