Olins A L, Olins D E
Science. 1974 Jan 25;183(4122):330-2. doi: 10.1126/science.183.4122.330.
Linear arrays of spherical chromatin particles (nu bodies) about 70 angstroms in diameter have been observed in preparations of isolated eukaryotic nuclei swollen in water, centrifuged onto carbon films, and positively or negatively stained. These bodies have been found in isolated rat thymus, rat liver, and chicken erythrocyte nuclei. Favorable views also reveal connecting strands about 15 angstroms wide between adjacent particles.
在将分离出的真核细胞核置于水中使其膨胀、离心到碳膜上并进行正染色或负染色的制备物中,已观察到直径约70埃的球形染色质颗粒(核小体)的线性阵列。这些颗粒已在分离出的大鼠胸腺、大鼠肝脏和鸡红细胞核中被发现。在有利的视野中还可看到相邻颗粒之间有宽度约为15埃的连接链。