Senior M B, Olins A L, Olins D E
Science. 1975 Jan 17;187(4172):173-5. doi: 10.1126/science.1111096.
Fragments of chromatin resembling the spheroid chromatin units (v bodies) have been isolated from formaldehyde-fixed and sonicated chicken erythrocyte nuclei. Ultracentrifugal analyses demonstrated that monomer v bodies have a molecular weight of about 300,000 per particle, exhibit a protein to DNA ratio (by weight) of 1.22:1, and contain a DNA fragment with a molecular weight of approximately 140,000 per v body.
已从甲醛固定并经超声处理的鸡红细胞核中分离出类似于球状染色质单位(v体)的染色质片段。超速离心分析表明,单体v体每个颗粒的分子量约为300,000,蛋白质与DNA的重量比为1.22:1,并且每个v体包含一个分子量约为140,000的DNA片段。