体内血小板聚集的研究：IV嘧啶并嘧啶衍生物的作用
Study of platelet aggregation in vivo: IV Effect of pyrimido-pyrimidine derivatives.
作者信息
Ambrus J L, Ambrus C M, Gastpar H, Thurber L, Miller R, Fretwell B, Lane K P
出版信息
J Med. 1977;8(5):287-94.
PMID:412904
Abstract
Two pyrimido-pyrimidine derivatives (RA 233 and VK 744) were found effective aggregation inhibitors in vitro of human and monkey platelets and in vivo in stumptailed monkeys and chimpanzees. They also inhibited thrombotic occlusion of metal screens inserted into arteriovenous shunts.
摘要
两种嘧啶并嘧啶衍生物（RA 233和VK 744）在体外对人和猴的血小板具有有效的聚集抑制作用，在体内对断尾猴和黑猩猩也有同样效果。它们还能抑制插入动静脉分流处的金属筛网的血栓形成。
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