Engström C, Linde A, Magnusson B C
J Oral Pathol. 1977 Nov;6(6):359-66. doi: 10.1111/j.1600-0714.1977.tb01801.x.
Different rat diets, deficient in calcium and/or vitamin D, were tested for varying experimental periods to obtain changes in serum calcium values, body weight gain and odontoblast-predentine morphology. One diet, R 25, used during a 14-day period, was found to induce lowered serum calcium values and an increased predentin width in incisor teeth. Rats fed this diet demonstrated an increase in alkaline phosphatase and ATP-splitting enzyme activity in dentinogenically active incisor odontoblasts. No other metabolic changes in these cells were demonstrated by the histochemical methods employed.
对不同的钙和/或维生素D缺乏的大鼠饮食进行了不同实验周期的测试，以观察血清钙值、体重增加和成牙本质细胞-前期牙本质形态的变化。一种饮食R 25在14天的时间段内使用，发现它会导致血清钙值降低和切牙的前期牙本质宽度增加。喂食这种饮食的大鼠在具有牙本质形成活性的切牙成牙本质细胞中，碱性磷酸酶和ATP分解酶活性增加。所采用的组织化学方法未显示这些细胞有其他代谢变化。
