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三氟胸苷(F3TDR)治疗中上皮再生抑制(作者译)

[Epithel regeneration inhibition in the treatment of Trifluorothymidin (F3TDR) (author's transl)].

作者信息

Holtmann H W, Stein H J

出版信息

Klin Monbl Augenheilkd. 1977 Oct;171(4):576-9.

PMID:412994
Abstract

After well-defined chemical and mechanical removal of the corneal epithelium from 38 rabbit eyes 19 right eyes were treated with F3TDR (Trifluorothymidine) 6 times daily, whereas the 19 left eyes were with physiologic NaCl-solution 6 times daily. The epithelial regeneration was compared with the contralateral controll-eye. No significant difference was found between both eye-series. The short-timed high dosage of F3TDR seems to have no delaying effect on epithelial regeneration.

摘要

在对38只兔眼进行明确的化学和机械性角膜上皮去除后,19只右眼每天用三氟胸苷(F3TDR)治疗6次,而19只左眼每天用生理氯化钠溶液治疗6次。将上皮再生情况与对侧对照眼进行比较。两组眼之间未发现显著差异。短时间高剂量的F3TDR似乎对上皮再生没有延迟作用。

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