Belloni M P, Cozzi R, De Marco A, Pichler G, Venezia O
Mutat Res. 1977 Nov;45(2):213-22. doi: 10.1016/0027-5107(77)90021-5.
The correlation between damage induced in somatic cells and that induced in germinal cells of the same genetic pool of individuals is important in establishing the possibility of extrapolation of this damage to the offspring. We have used Drosophila melanogaster to compare cytologically the frequency of aberrations induced in the cells of somatic ganglia and in the spermatocytes I of males irradiated with 625 R X-rays. The spermatocytes were more sensitive than the gangliar cells to radiation: the aberrations induced in the spermatocytes I were three times more frequent than those induced in the ganglia. The distribution of the aberrations was, however, similar. The most important variable element lies in our observing no symmetrical exchanges in the spermatocytes. This result seems to us to be related to the fact that in the males of D. melanogaster there is no crossing-over.
在同一个体的基因库中，体细胞损伤与生殖细胞损伤之间的相关性对于确定将这种损伤外推至后代的可能性至关重要。我们利用黑腹果蝇，通过细胞学方法比较了经625伦琴X射线照射的雄性个体的体神经节细胞和初级精母细胞中诱导产生的畸变频率。初级精母细胞比神经节细胞对辐射更敏感：初级精母细胞中诱导产生的畸变频率是神经节中诱导产生的畸变频率的三倍。然而，畸变的分布是相似的。最重要的可变因素在于我们在初级精母细胞中未观察到对称交换。在我们看来，这一结果与黑腹果蝇雄性个体中不存在交叉互换这一事实有关。
