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[γ辐射在黑腹果蝇辐射敏感突变系体细胞中诱导的染色体畸变]

[Chromosome aberrations induced by gamma radiation in the somatic cells of a radiosensitive mutant line of Drosophila melanogaster].

作者信息

Levina V V, Malinovskiĭ O V, Zakharov I A

出版信息

Genetika. 1980;16(2):285-9.

PMID:6766426
Abstract

Chromosome aberrations induced by gamma-rays in ganglia cells of Drosophila melanogaster larvae have been studied. Two strains of Drosophila were used: radiosensitive mutant rad (2) 201G1 and normal strain. It has been shown that the frequency of cells with chromosome aberrations in radiosensitive larvae is much more than in normal larvae after gamma-irradiation. The ratio of chromosome and chromatid deletions number to the number of exchange type aberrations is the same for both strains. The kinetics of chromosome aberrations induced in rad-larvae is similar to the normal one. The conclusion has been made that the realization of rad (2) 201G1 mutation takes place on the cell level.

摘要

对γ射线诱导的黑腹果蝇幼虫神经节细胞染色体畸变进行了研究。使用了两种果蝇品系:辐射敏感突变体rad(2)201G1和正常品系。结果表明,γ射线照射后,辐射敏感幼虫中具有染色体畸变的细胞频率远高于正常幼虫。两种品系中染色体和染色单体缺失数与交换型畸变数的比率相同。rad幼虫中诱导的染色体畸变动力学与正常情况相似。得出的结论是,rad(2)201G1突变在细胞水平上发生。

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