• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

大鼠被动回避学习与右旋苯丙胺剂量和电击强度的关系。

Passive avoidance learning in the rat as functions of d-amphetamine dosage and shock intensity.

作者信息

Seliger D L

出版信息

Psychopharmacology (Berl). 1977 Nov 15;54(3):241-2. doi: 10.1007/BF00426570.

DOI:10.1007/BF00426570
PMID:413139
Abstract

The effects of d-amphetamine dosage (0, 1, 3, and 5 mg/kg) and shock intensity (0.2, 0.5, and 0.8 ma) on the learning of a passive avoidance response were assessed in rats. A curvilinear dose-response relationship was found at all shock levels, showing slower learning under moderate doses of d-amphetamine. The lowest shock level produced slower learning, especially in conjunction with the lowest dose of d-amphetamine. Results are discussed in terms of freezing behavior.

摘要

研究评估了d-苯丙胺剂量(0、1、3和5毫克/千克)和电击强度(0.2、0.5和0.8毫安)对大鼠被动回避反应学习的影响。在所有电击水平下均发现了曲线剂量反应关系,表明中等剂量的d-苯丙胺会导致学习速度减慢。最低的电击水平导致学习速度减慢,尤其是与最低剂量的d-苯丙胺共同作用时。根据僵住行为对结果进行了讨论。

相似文献

1
Passive avoidance learning in the rat as functions of d-amphetamine dosage and shock intensity.大鼠被动回避学习与右旋苯丙胺剂量和电击强度的关系。
Psychopharmacology (Berl). 1977 Nov 15;54(3):241-2. doi: 10.1007/BF00426570.
2
Dose-response effects of d-amphetamine on passive avoidance learning in the rat.右旋苯丙胺对大鼠被动回避学习的剂量反应效应。
Psychopharmacologia. 1975 Oct 31;44(2):191-3. doi: 10.1007/BF00421009.
3
Anorexic and behavioural effects of a new imidazo-isoindole derivative (mazindol) in comparison with d-amphetamine in the rat.
Pharmacology. 1977;15(1):46-56. doi: 10.1159/000136662.
4
REDUCTION OF FREEZING BEHAVIOR AND IMPROVEMENT OF SHOCK AVOIDANCE BY D-AMPHETAMINE.右旋苯丙胺对冻结行为的减少及回避电击能力的改善
J Comp Physiol Psychol. 1965 Aug;60:36-40. doi: 10.1037/h0022302.
5
Effects of d-amphetamine on responding simultaneously maintained and punished by presentation of electric shock.右旋苯丙胺对电击呈现同时维持和惩罚反应的影响。
Psychopharmacology (Berl). 1977 Oct 20;54(2):119-24. doi: 10.1007/BF00426766.
6
An analysis of D-amphetamine produced facilitation of avoidance acquisition in rats and performance changes subsequent to drug termination.
Life Sci. 1974 Jan 1;14(1):163-80. doi: 10.1016/0024-3205(74)90256-2.
7
Effects of intraperitoneal and intraventricular d-amphetamine administration on active avoidance performance in the rat.腹腔注射和脑室内注射d-苯丙胺对大鼠主动回避行为的影响。
Life Sci. 1973 Dec 1;13(11):1573-80. doi: 10.1016/0024-3205(73)90146-x.
8
Amphetamine: effects on defensive flight or avoidance in the rat.
Pharmacol Biochem Behav. 1979 Sep;11(3):325-9. doi: 10.1016/0091-3057(79)90143-6.
9
Effects of d-amphetamine and cocaine on repeated acquisition with timeout from avoidance.右旋苯丙胺和可卡因对有回避超时的重复习得的影响。
Pharmacol Biochem Behav. 1978 Nov;9(5):659-63. doi: 10.1016/0091-3057(78)90218-6.
10
Effects of D-amphetamine on defensive behaviors related to fear and anxiety.
Pharmacol Biochem Behav. 2006 Apr;83(4):490-9. doi: 10.1016/j.pbb.2006.03.009. Epub 2006 Apr 19.

引用本文的文献

1
Brain Angiotensin II AT1 receptors are involved in the acute and long-term amphetamine-induced neurocognitive alterations.脑内血管紧张素II 1型受体参与了苯丙胺引起的急性和长期神经认知改变。
Psychopharmacology (Berl). 2016 Mar;233(5):795-807. doi: 10.1007/s00213-015-4153-1. Epub 2015 Nov 28.
2
Pre- and postnatal exposure to kynurenine causes cognitive deficits in adulthood.孕前期和孕后期暴露于犬尿氨酸会导致成年期认知缺陷。
Eur J Neurosci. 2012 May;35(10):1605-12. doi: 10.1111/j.1460-9568.2012.08064.x. Epub 2012 Apr 20.
3
Passive avoidance in rats: disruption by dopamine applied to the nucleus accumbens.

本文引用的文献

1
Facilitation of instrumental avoidance learning by amphetamine: an analysis.
Psychopharmacologia. 1968;13(5):418-25. doi: 10.1007/BF00404957.
2
Amphetamine induced selective stimulation of certain behaviour items with concurrent inhibition of others in an open-field test with rats.在对大鼠的旷场试验中,苯丙胺引起对某些行为项目的选择性刺激,同时抑制其他行为项目。
Behaviour. 1971;39(1):1-17.
3
The dose-response effect of amphetamine upon avoidance behaviour in the rat seen as a function of increasing stereotypy.安非他命对大鼠回避行为的剂量反应效应表现为刻板行为增加的函数。
大鼠的被动回避:伏隔核应用多巴胺导致的破坏作用。
Psychopharmacology (Berl). 1984;83(1):70-5. doi: 10.1007/BF00427425.
Psychopharmacologia. 1972;23(4):334-47. doi: 10.1007/BF00406736.
4
Dose-response effects of d-amphetamine on passive avoidance learning in the rat.右旋苯丙胺对大鼠被动回避学习的剂量反应效应。
Psychopharmacologia. 1975 Oct 31;44(2):191-3. doi: 10.1007/BF00421009.