Henry K, Bird R G, Doe W F
Br Med J. 1974 Mar 23;1(5907):542-3. doi: 10.1136/bmj.1.5907.542.
During an ultrastructural study of small-intestinal mucosa from a patient suffering from alpha-chain disease organisms were identified within the epithelial cytoplasm which showed the fine structural features of the coccidian group. Though coccidiosis is well recognized as causing a diarrhoeal and often lethal illness in animals it has been neglected as a cause of disease in man. Thus this finding may be significant and warrants further investigation into its possible role in the pathogenesis of alpha-chain disease.
在对一名患有α链病患者的小肠黏膜进行超微结构研究时,在上皮细胞质内发现了一些生物体,这些生物体呈现出球虫类群的精细结构特征。尽管球虫病在动物中被公认为会引发腹泻且常常是致命疾病,但它作为人类疾病的病因却一直被忽视。因此,这一发现可能具有重要意义,值得进一步研究其在α链病发病机制中可能发挥的作用。