Hutchison W M, Dunachie J F, Siim J C, Work K
Br Med J. 1970 Jan 17;1(5689):142-4. doi: 10.1136/bmj.1.5689.142.
Specific pathogen-free domestic cats were fed with tissue cysts containing Toxoplasma gondii. In two infected cats large numbers of oocysts were produced in the faeces; no oocysts were observed in the faeces of the uninfected control cat. Five days after the feeding of the toxoplasms profuse schizogonic and gametogonic stages were observed in the epithelial cells of the small intestine of one infected cat. A single schizont was observed in an intestinal epithelial cell of a second cat six days after being fed the tissue cysts. There was no evidence of schizogony or gametogony in the uninfected control cat. The stages observed in the intestinal epithelium are identical with those of the well-known endogenous cycles of coccidian parasites. The appearance of these stages, together with the nature of the oocyst, indicates that T. gondii is a coccidian parasite closely related to the genus Isospora.
将无特定病原体的家猫喂食含有刚地弓形虫组织包囊的食物。在两只受感染的猫中，粪便中产生了大量卵囊；未感染的对照猫粪便中未观察到卵囊。喂食弓形虫五天后，在一只受感染猫的小肠上皮细胞中观察到大量裂殖生殖和配子生殖阶段。在喂食组织包囊六天后，在第二只猫的肠上皮细胞中观察到一个单个裂殖体。未感染的对照猫没有裂殖生殖或配子生殖的迹象。在肠上皮中观察到的阶段与球虫寄生虫著名的内源性周期阶段相同。这些阶段的出现以及卵囊的性质表明，刚地弓形虫是一种与等孢属密切相关的球虫寄生虫。
