使用肌肉松弛剂和间歇性正压通气治疗新生儿破伤风。

Treatment of tetanus neonatorum with muscle relaxants and intermittent positive-pressure ventilation.

作者信息

Smythe P M, Bowie M D, Voss T J

出版信息

Br Med J. 1974 Feb 9;1(5901):223-6. doi: 10.1136/bmj.1.5901.223.

DOI:10.1136/bmj.1.5901.223

PMID:4131848

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1633113/

Abstract

Intermittent positive-pressure ventilation and muscle relaxants were first used in Cape Town in 1958 in an attempt to reduce the mortality from tetanus neonatorum, which was then over 90%. Problems of effective ventilation, of tracheostomy, and of infection in the neonate were gradually overcome so that between 1967 and 1972 the mortality in 186 cases was 21%. In a consecutive series of 97 cases the mortality was 10%.

摘要

1958年，间歇性正压通气和肌肉松弛剂首次在开普敦使用，旨在降低新生儿破伤风的死亡率，当时该死亡率超过90%。新生儿有效通气、气管切开术及感染等问题逐渐得到解决，因此在1967年至1972年期间，186例患者的死亡率为21%。在连续的97例病例中，死亡率为10%。