环境碳氢化合物会导致猫的下丘脑和视束发生退化。
Environmental hydrocarbons produce degeneration in cat hypothalamus and optic tract.
作者信息
Schaumburg H H, Spencer P S
出版信息
Science. 1978 Jan 13;199(4325):199-200. doi: 10.1126/science.413192.
PMID:413192
Abstract
2,5-Hexanedione, the principal neurotoxic metabolite of the industrial solvents n-hexane and methyl n-butyl ketone causes axonal degeneration in the mammillary body and visual nuclei of cats. Prolonged, low-level exposure to hydrocarbons in the environment may cause premature deterioration in areas of the human brain vital for perception and behavior.
摘要
2,5 - 己二酮是工业溶剂正己烷和甲基正丁基酮的主要神经毒性代谢产物，可导致猫的乳头体和视觉核中的轴突退化。长期低水平接触环境中的碳氢化合物可能会导致对人类感知和行为至关重要的大脑区域过早退化。
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