Dickson A, Birchmore B
Acta Haematol. 1977;58(5):298-306. doi: 10.1159/000207841.
54 our of 112 patients with leukaemia have been shown to produce a lymphocytotoxin in their serum when the number of malignant cells present in the peripheral blood was considerably raised but the normal blood cells were low. This lymphocytotoxin reacts with all normal cells. It is a high molecular weight protein, though not an antibody. Partial purification was achieved by elution from DEAE-52-cellulose at about pH 6.9.
112例白血病患者中，有54例在其外周血中存在的恶性细胞数量显著增加而正常血细胞数量减少时，被证明血清中会产生淋巴细胞毒素。这种淋巴细胞毒素可与所有正常细胞发生反应。它是一种高分子量蛋白质，但不是抗体。通过在约pH 6.9的条件下从DEAE - 52纤维素上洗脱实现了部分纯化。
