Dickson A
Br Med J. 1972 Oct 28;4(5834):209-11. doi: 10.1136/bmj.4.5834.209.
Fifteen out of 51 patients with leukaemia have produced a lymphocytotoxin in their serum which reacts with their own and a high percentage of all other lymphocytes. This is probably a protein, but not an antibody. It has been detected only before or early during cytotoxic treatment, or during a relapse. It is postulated that the lymphocytotoxin is a specific protein produced by the leukaemic cells, which may facilitate their spread in the body.
51例白血病患者中有15例血清中产生了淋巴细胞毒素,该毒素能与自身以及大部分其他淋巴细胞发生反应。这可能是一种蛋白质,但不是抗体。仅在细胞毒性治疗前或治疗早期,或复发期间检测到该毒素。据推测,淋巴细胞毒素是白血病细胞产生的一种特异性蛋白质,可能有助于其在体内扩散。