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氰基丙烯酸异丁酯(丁酯)用于闭塞胃冠状静脉和食管静脉曲张

Isobutyl 2-cyanoacrylate (bucrylate) in obliteration of gastric coronary vein and esophageal varices.

作者信息

Lunderquist A, Börjesson B, Owman T, Bengmark S

出版信息

AJR Am J Roentgenol. 1978 Jan;130(1):1-6. doi: 10.2214/ajr.130.1.1.

Abstract

Percutaneous transhepatic portography was performed in 22 patients with liver cirrhosis and portal hypertension. All patients had bled or were bleeding from presumed esophageal varices. One or more veins feeding esophageal varices were occluded with bucrylate. Follow-up examination in eight patients 1-12 months later showed recanalization of previously obliterated veins in six; however, these veins were markedly smaller than before the procedure. In patients where veins were still occluded, new veins had opened up and carried blood to the esophageal varices, which were filled to a lesser degree than before. In our experience, bucrylate is superior to Gelfoam, thrombin, and Etolein in producing venous occlusion.

摘要

对22例肝硬化门静脉高压患者进行了经皮经肝门静脉造影。所有患者均有或正从推测的食管静脉曲张出血。用丁苯氰酯闭塞一条或多条为食管静脉曲张供血的静脉。1至12个月后对8例患者进行随访检查,结果显示6例患者先前闭塞的静脉再通;然而,这些静脉明显比手术前细小。在静脉仍闭塞的患者中,有新的静脉开放并将血液输送至食管静脉曲张,但其充盈程度低于术前。根据我们的经验,在造成静脉闭塞方面,丁苯氰酯优于明胶海绵、凝血酶和依托前列素。

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